RESUMO
The ingredients of compound "Baxianjiangtang" are Radix Rehmanniae, Radix Polygoni Multiflori preparate, Rodix Astragali, Radix Ophiopogonis etc. Pharmacological tests showed that it can decrease LPO and increase the activity of SOD in blood and liver of Alloxan induced diabetic rats and mice.It also increased that phagocytosis of phagocytes of experimental anim als. It can increased tolerance to fatigue at low and high temperature conditions. According tothe above results, it can be considered as safe and effective.
RESUMO
Objective: To observe the effect of carboxyl-amino-polysaccharide on the gastric ulcer. Methods: Various rat models of gastric ulcer were established respectively by ethanol, aspirin, hydrochloric acid, acetic acid and bound stress in water bath. Results: Inhibitory rates of carboxyl polysaccharide in the dose of 0.5, 0.33, 0.17g/kg were 42.09%, 35.55%and 33.53%for the ethanol-induced model; 53.65%, 49.48%, and 49.76%for the aspirin-induced model; 51.48%, 44.09%, and 33.64%for the hydrochloric-acid-induced model, 49.44%, 46.23%, and 45.10%for the acetic-acid-induced model and 50.12%, 44.63%and 41.92%for the bound-stress-induced model respectively. Conclusion: Carboxyl-amino-polysaccharide can prevent and treat gastric ulcer. Its effect is similar to that of denol, famotidine and cimetidine.