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Ancestry composition of populations and individuals has been extensively investigated in recent years due to advances in the genotyping and sequencing technologies. As the number of populations and individuals used for ancestry inference increases remarkably, say more than 100 populations or 1000 individuals, it is usually challenging to present the ancestry composition in a traditional way using a rectangular graph. To address this issue, we developed a program, AncestryPainter, which can illustrate the ancestry composition of populations and individuals with a rounded and nice-looking graph to save space. Individuals are depicted as length-fixed bars partitioned into colored segments representing different ancestries, and the population of interest can be highlighted as a pie chart in the center of the circle plot. In addition, AncestryPainter can also be applied to display personal ancestry in a way similar to that for displaying population ancestry. AncestryPainter is publicly available at http://www.picb.ac.cn/PGG/resource.php.
Assuntos
Humanos , Gráficos por Computador , Genética Populacional , SoftwareRESUMO
OBJECTIVE To study the clinical efficacy of voice training on voice recovery in patients with vocal cord polyps during perioperative period.METHODS A total of 72 patients with vocal cord polyp were chosen in this study and they were randomly divided into study group and control group. After operation, the control group received routine treatment, and the study group received voice training on the basis of routine treatment. The results of voice acoustic analysis in the two groups were compared at 8 weeks after operation.RESULTS After 8 weeks, the maximum phonation time(MPT), dysphonia severity index (DSI) and the highest frequency(F0-High) of the study group were significantly higher than that of control group (P0.05).CONCLUSION Voice training in the early postoperative period of vocal cord polyps was helpful to the recovery of the voice.
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Objective To discuss the clinical curative effect on maxillary sinusitis nasal endoscopic single path surgical treatment and provide reference for the clinical treatment.Methods A total of 52 patients of fungal ball type maxillary sinusitis were randomly divided into group A(26 patients) and group B (26 patients).The patients in group A were treated by endoscopic single path surgical treatment and the patients in group B were treated by intranasal antrostomy.The clinical curative effect was analyzed.Results In group A and group B,the total effective rate was 88.5％(23/26) and 65.4％(17/26),there was significant difference (P ＜0.05).The remission rate of nasal obstruction,nasal discharge with suppuration,nasal discharge with blood,headache were 100.0％ (26/26),92.3 ％ (24/26),84.6％ (22/26),73.1％ (19/26) in group A,and 100.0％(26/26),88.5％(23/26),76.9％(20/26),65.4％(17/26) in group B.The recurrence rate in group A and group B was 0,15.4％(4/26),there was significant difference (P＜ 0.05).Conclusions The clinical curative effect of endoscopic single path surgical treatment is better,and the recurrence rate is lower.It is worthy of clinical application.
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Genetic admixture in human, the result of inter-marriage among people from different well-differentiated populations, has been extensively studied in the New World, where European colonization brought contact between peoples of Europe, Africa, and Asia and the Amerindian populations. In Asia, genetic admixing has been also prevalent among previously separated human populations. However, studies on admixed populations in Asia have been largely underrepresented in similar efforts in the New World. Here, I will provide an overview of population genomic studies that have been published to date on human admixture in Asia, focusing on population structure and population history.