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1.
Asian Journal of Andrology ; (6): 433-437, 2019.
Artigo em Chinês | WPRIM | ID: wpr-842525

RESUMO

Prostate cancer is the most common malignancy in the reproductive system of older males. Androgen deprivation therapy (ADT) is an important treatment for prostate cancer patients. However, almost all prostate cancer patients unavoidably progress to the castration-resistant stage after ADT treatment. Recent studies have shown that tumor-associated immune cells play major roles in the initiation, progression, and metastasis of prostate cancer. Various phenotypes of tumor-associated immune cells have tumor-promoting or antitumor functions mediated by interacting with tumor cells. Here, we review the current knowledge of tumorassociated immune cells in prostate cancer.

2.
Asian Journal of Andrology ; (6): 433-437, 2019.
Artigo em Inglês | WPRIM | ID: wpr-1009744

RESUMO

Prostate cancer is the most common malignancy in the reproductive system of older males. Androgen deprivation therapy (ADT) is an important treatment for prostate cancer patients. However, almost all prostate cancer patients unavoidably progress to the castration-resistant stage after ADT treatment. Recent studies have shown that tumor-associated immune cells play major roles in the initiation, progression, and metastasis of prostate cancer. Various phenotypes of tumor-associated immune cells have tumor-promoting or antitumor functions mediated by interacting with tumor cells. Here, we review the current knowledge of tumor-associated immune cells in prostate cancer.


Assuntos
Humanos , Masculino , Progressão da Doença , Linfócitos do Interstício Tumoral/patologia , Macrófagos/patologia , Neutrófilos/patologia , Neoplasias da Próstata/terapia , Neoplasias de Próstata Resistentes à Castração/terapia
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