The advantage and disadvantage of transoral orbotic surgery for parapharyngeal tumors: a systemic review / 中华耳鼻咽喉头颈外科杂志

Parapharyngeal space tumors are rare. According to the size, location, relationship with the vascular nerves, benign and malignant tumors, different surgical approaches are used. This article reviews surgical techniques, indications, complications and current advantages and disadvantages of transoral robotic surgery (TORS) for resection of parapharyngeal space tumors. To provide reference for the application of TORS in parapharyngeal space tumor surgery.

Laryngopharyngeal reflux disease and laryngeal precancerous lesions / 中华耳鼻咽喉头颈外科杂志

The laryngopharyngeal reflux disease (LPRD) is a general term for a series of symptoms and signs caused by reflux of the stomach contents to the upper part of the esophageal sphincter. In recent years, the laryngopharyngeal reflux (LPR) is getting more and more attention as laryngeal precancerous lesions and risk factors of laryngeal cancer. Laryngeal precancerous lesions plays a important role in the development of laryngeal cancer process. This article will review the role and mechanisms of LPR in the laryngeal precancerous lesions, and the status of anti-reflux in the treatment of laryngeal precancerous lesions.

Clinical analysis of imflammatory myofibroblastic tumor of the nasal cavity and paranasal sinus / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To investigate the clinical features, therapeutic methods and therapeutic efficacy of imflammatory myofibroblastic tumor(IMT)of the nasal cavity and paranasal sinuses.@*METHOD@#Clinical data of 14 cases diagnosed as IMT by pathology were retrospectively analyzed. There were 8 males and 6 females,age ranging from 18 to 77 years. 12 cases of them were treated by surgery while 2 cases received postoperative radiotherapy.@*RESULT@#All cases were operated. All the patients were followed up for a period of 1 to 7 years after operation and two cases were proved low grade IMT pathologically. Eight cases survived with no recurrence until the last follow-up and 6 cases relapsed, of which 4 cases died and 2 were alive with tumor.@*CONCLUSION@#IMT of the nasal cavity and paranasal sinuses is very rare. The diagonosis of IMT is based on pathology and immunohistochemistry. Proper diagnosis is essential to avoid mutilating and disfiguring surgical procedures. Radical excision is still the first choice of treatment for IMT of the nasal cavity and paranasal sinuses. Chemotherapy and radiotherapy may not be helpful to prevent recurrence after operation. Due to high recurrence rate, long-term follow up is necessary after operation.

Clinical analysis of nasal and laryngeal neuroendocrine carcinoma / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To investigate the clinicopathological features, therapeutic methods and therapeutic effects of neuroendocrine carcinoma in nasal and laryngeal region.@*METHOD@#Six cases with neuroendocrine carcinoma of the nose and the larynx were analyzed retrospectively. All cases were proved by pathology and immunohistochemistry. One case was treated by only radiotherapy, and five cases by combined treatment (surgery followed by radiotherapy and chemotherapy).@*RESULT@#All the patients were followed up for a period of 11-84 months. Two cases showed recurrence after operation. Three cases occurred cervical lymph node metastasis, of which 2 cases received neck dissection and 1 case received chemotherapy and radiotherapy due to no surgical indications. Three cases occurred local recurrence, cervical lymphadenopathy, liver or lung metastases. Until the last follow up, four patients died of tumor, while two patients lived with no evidence of disease.@*CONCLUSION@#Nasal and laryngeal neuroendocrine carcinoma is composed of a group of different morphology and prognosis lesions. Corrent diagnosis depends on clinical characteristic, electron microscopic and immunohistochemical examination. CT and MRI examination could be helpful to understand the extent of disease and lesion nature. The prognosis and treatment method of neuroendocrine carcinoma were vary with different pathological types. Combined treatment based on surgery should be adopted to the disease.

Clinical analysis of the primary nasal septum mass in 253 cases / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To study the methods of the surgical treatment for the nasal septum mass.@*METHOD@#Two hundred and fifty-three cases of nasal septum mass were treated by surgery in our department from March 1983 to August 2007. Their clinical data were retrospectively analyzed.@*RESULT@#After follow-up, most cases had no postoperative recurrence of nasal obstruction and epistaxis.@*CONCLUSION@#If the diagnosis was confirmed, the effect of the surgical treatment for the nasal septum benign tumor is satisfactory. Follow-up should be done in cases with malignant tendency and malignant tumors.