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1.
Artigo | IMSEAR | ID: sea-223660

RESUMO

Background & objectives: Zinc is a crucial micronutrient in adolescence, required for promoting growth and sexual maturation. Adolescents of some tribes may be at high risk of zinc deficiency due to dietary inadequacy and poor bioavailability of zinc from plant-based diets. This study aimed to evaluate the risk of zinc deficiency by estimating prevalence of inadequate zinc intake, prevalence of low serum zinc and stunting among tribal adolescents. Methods: A cross-sectional community-based survey was conducted among adolescents (10-19 yr) in three purposively selected districts where Bhil, Korku and Gond tribes were in majority. Structured data collection instrument comprising information about sociodemographic characteristics and dietary recall data was used. Anthropometric assessment was conducted by standardized weighing scales and anthropometry tapes, and blood sample was collected from antecubital vein into trace element-free vacutainers. Serum zinc was estimated using an atomic absorption spectrophotometer. Results: A total of 2310 households were approached for participation in the study, of which 2224 households having 5151 adolescents participated. Out of these enlisted adolescents, 4673 responded to dietary recall (90.7% response rate). Anthropometry of 2437 participants was carried out, and serum zinc was analyzed in 844 adolescents. The overall prevalence of dietary zinc inadequacy was 42.6 per cent [95% confidence interval (CI) 41.2 to 44.1] with reference to the estimated average requirement suggested by International Zinc Nutrition Consultative Group (IZiNCG) and 64.8 per cent (95% CI 63.4 to 66.2) with Indian Council of Medical Research-recommended requirements. Stunting was observed in 29 per cent (95% CI 27.2 to 30.8) participants. According to IZiNCG cut-offs, low serum zinc was detected in 57.5 per cent (95% CI 54.1 to 60.8) of adolescents, whereas it was 34.4 per cent (95% CI: 31.2-37.5) according to the national level cut-off. Interpretation & conclusions: Risk of dietary zinc inadequacy and low serum zinc concentration amongst adolescents of the Gond, Bhil and Korku tribes is a public health concern.

2.
J Cancer Res Ther ; 2019 Oct; 15(5): 1212-1215
Artigo | IMSEAR | ID: sea-213510

RESUMO

Purpose: The study purpose included dosimetric comparison of cobalt 60 (60Co) and iridium 192 (192Ir) high dose rate (HDR) source used in brachytherapy treatment of cervical cancer. Materials and Methods: Computed tomography (CT) scans for 15 patients of carcinoma of uterine cervix using 3-mm slice thickness were considered for the study The contouring of high-risk clinical target volume (HRCTV), bladder, and rectum on CT images was done as per the GEC ESTRO guidelines with the help of magnetic resonance imaging images in the treatment planning system. All parameters were kept the same for 60Co (3.5 mm active length, 0.5 mm active dia, Bebig) and 192Ir (3.5 mm active length, 0.6 mm active dia, Bebig) HDR source with 2.5-mm step size and dose prescription to Point A. As per the International Commission on Radiation Unit (ICRU)-89 guidelines, the dose–volume parameters such as D50(Gy), D90(Gy), and D98(Gy) for HRCTV and D0.1cc (Gy), D1cc (Gy), D2cc (Gy), and D5cc (Gy) to the bladder and rectum were calculated for both the HDR sources. Results: The difference in dose–volume histogram parameters such as D50,D90,and D98 of HRCTV was 3.19%, 1.13%, and 0.50%, respectively, for the two radioisotopes. The difference in dose values of D0.1cc, D1cc, D2cc, D5cc, and ICRU reference points of bladder was –0.58%, –0.67%, –0.99%, –0.94%, and –1.75%, respectively. On the other hand, dose difference for D0.1cc, D1cc, D2cc, D5cc, and ICRU reference points of rectum was 0.67%, 0.26%, 0.56%, 0.63%, and –0.33%, respectively. Conclusions: The present study results show that all the dose parameters of HRCTV, bladder, and rectum with 60Co were comparable with those of 192Ir HDR source. The isodose distribution is more bulge out for 60Co in cranial-caudal direction compared to that of 192Ir. However, these differences can be reduced by treatment planning optimization techniques. The clinical plan evaluation in each slice and plane is necessary to explore the logistic and financial benefits of miniaturized 60Co source over 192Ir HDR source

3.
Artigo | IMSEAR | ID: sea-211390

RESUMO

Background: To study the various advance technology for the diagnosis of Traumatic Brain Injury (TBI) and find out Emerging trends occur in TBI (Traumatic Brain Injury) patients.Methods: The present study was conducted with 500 patients, age between 02 year to 70 years mean age (36 Years) presenting to emergency department of Uttar Pradesh University of Medical Sciences, Saifai, Etawah, with a history of acute head trauma from January 2016 to December 2018. All patients were examined using 64 slices MDCT and 1.5T MRI Scanner also.Results: Traumatic brain injury caused by various reasons like 62.1% road traffic accidents (RTA) and 25.1% fall from height (FFH) being and 11.83% Assault/hit by hard object and 0.88% are gunshot injury. Loss of consciousness was the most common complaint of the 59.1% TBI patients followed by 17.75% Vomiting and headache, 11.83% facial injury and 11.24% scalp injury. All TBI patients were diagnosed by MDCT 64 Slices Somatom Sensation Scanner who was observed 41.42% skull fractures, 29.28% extra dural hematoma, 27.21% sub dural hematoma, 23.96% sub archnoid haemorrhage, 13% intra cerebral hematoma, 30.17% brain contusions and 24.26% diffuse cerebral edema.Conclusions: Road traffic accidents remain the leading cause of trauma in our country. MRI and MDCT are well recognized method to know the extent and various types of hemorrhages and skull fractures in TBI patients. The present study data is indicated 62.1% majority of TBI patients are suffered by Road traffic accidents mainly young males with alcoholism.

4.
Indian J Exp Biol ; 2014 Jun; 52(6): 650-657
Artigo em Inglês | IMSEAR | ID: sea-153744

RESUMO

Manganese deficiency in wheat has become an important nutritional disorder particularly in alkaline calcareous soils where rice-wheat rotation is followed. This experiment was aimed to study the mechanism of Mn efficiency during various developmental stages in six wheat cultivars grown at two Mn levels viz. 0 and 50 mg Mn kg-1soil (Mnapplied as MnSO4.H20) in pots. The Mn vegetative efficiency calculated on the basis of shoot dry weight at anthesis indicated HD 2967 and PBW 550 (bread wheat) as Mn efficient and durums as Mn inefficient. The efficient cultivars recorded highest values for influx, uptake, shoot dry weight, leaf area/plant, SPAD index, Fv/Fmratio and root length that explained their higher efficiencies whereas inefficiency of durum cultivars was attributed to their smaller roots and lower influx. Under Mn deficiency, PDW 314 and PDW 291 retained 68% and 64%, respectively, of total Mn uptake in vegetative parts (stem and leaves) and lowest in grains 7% and 5%, respectively, whereas PBW 550, BW 9178 and HD 2967 retained 29, 37 and 34% in vegetative parts, and 21, 17 and 15 % in grains, respectively at maturity. Higher utilization efficiency of efficient genotypes also indicated that increased Mn uptake with Mn supply produced more efficiently grains in efficient genotypes but vegetative parts in inefficient genotypes. Hence Mn efficiency of a cultivar could be explained by longer roots, higher uptake, influx and efficiency index during vegetative phase and higher grain yield and utilization efficiency during generative phase.


Assuntos
Genótipo , Manganês/análise , Manganês/metabolismo , Oryza/metabolismo , Folhas de Planta/genética , Folhas de Planta/metabolismo , Raízes de Plantas/genética , Raízes de Plantas/metabolismo , Solo/química , Triticum/genética , Triticum/metabolismo
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