RESUMO
At present, the artificial materials for cranial repair include methylsilicone rubber, titanium net, bonwe cement and stainless steel sil net, etc. Titanium net, organic glass, methylsilicone rubber and bone cement are easy to operate, but they are not satisfactory as an ideal material of repairing cranial defects because they only contributes to partial functional alternation as a foreign implant. High cost and long periodicity of tissue engineered bone lead to limit its application in clinics as an ideal repair material of bone defects. With the advanced development of biomaterials study and the deeper manufacture of industrialized tissue engineered products, this technology will achieve a large-scale application of clinical practice.
RESUMO
Objective:To approach the actions of survivin and COX-2 during the genesis and development in brain astrocytoma and whether they have dependablity each other.Methods:The expression of survivin and COX-2 was examined by immunohistochemistry SP and their interrelationship was analyzed.Results:The positive expressive rates of survivin in astrocytoma gradeⅠ,Ⅱ,Ⅲ and Ⅳsubgroups were shown in an increased tendency.The expression was weak positive in higher differentiation group,and the positive expressive rate of survivin was increased in the lower differentiation group.There was an significant difference between these two groups(?2=11.20,P