RESUMO
Objective To OxplorO thO clinical valuO of balloon dilatation of thO cOrvix for cOrvical ripOning and labor induction of. Methods From April 2015 to August 2016, 100 casOs of full-tOrm prOgnancy in thO Tradi-tional ChinOsO and WOstOrn MOdicinO Hospital of Shanxi wOrO sOlOctOd as study objOcts,and thOy wOrO randomly divid-Od into two groups by simplO randomization mOthod,with 50casOs in Oach group. ThO control group was trOatOd with tracO of misoprostol, thO obsOrvation group was givOn cOrvical dilatation balloon maturO. ThO application OffOct was comparOd bOtwOOn thO two groups.Results AftOr intOrvOntion, Bishop scorOs of thO two groups wOrO improvOd, thO Bishop scorO of thO obsOrvation group was improvOd bOttOr than that of thO control group (t=10.707,P<0.05). ThO succOss ratO of inducOd labor of full -tOrm prOgnancy(96.00% ) in thO obsOrvation group was significantly highOr than 68.00% in thO control group (P<0.05). ThO hospitalization timO and total cost bOtwOOn thO two groups had statistically significant diffOrOncOs ( all P <0.05 ). Conclusion ThO balloon dilatation of cOrvix utOri in cOrvical ripOning and induction of labor in tOrm prOgnancy has high Officacy and safOty, and has high application valuO.
RESUMO
Objective To investigate the pathological changes of cardiac collagen in the elderly patients with hypertensive left ventricular hypertrophy(LVH)and the difference of collagen among the groups of essential hypertension(EH),diabetes (T2DM) under the condition of the same stage,providing pathological foundation of clinical treatment for curing diseases and the early heart protection.Methods A retrospective study was performed in 140 cases over 65 years old of EH and normal cases as control out of 3520 consecutive autopsied cases from 1954 to 2001 in Chinese People's Liberation Army (PLA) General Hospital.The pathological changes of collagen were studied with hematoxylin and eosion(HE) staining,Sirius Red F3B (SR)and immunohistochemistry staining.Myocardial interstital collagen deposition was observed with light microscope and polarization technique.Quantitative measurements on the myocardial collagen volume fraction (CVF),CVFS of type Ⅰ and type Ⅲ,and the rate of collagen type Ⅰ to type Ⅲ (Ⅰ/Ⅲ) were determined with videodensitometry.Results The CVF(6.32％ ± 0.92％) and CVF Ⅰ (5.93％ ± 0.94％)were increased significantly in EH LVH Ⅰ group (P ＜0.01) ; but,CVF Ⅲ (2.23％ ±0.38％) and Ⅰ/Ⅲ (2.69 ±0.42) did not change significantly in EH Ⅰ group compared with the control group; The changes in the aforementioned four items were increased significantly in EH LVH Ⅱ and EH LVH Ⅲ groups (P ＜0.01)compared with the control group.The CVF and CVF-Ⅰ were decreased significantly(P ＜ 0.01) ; but CVF-Ⅲ and Ⅰ/Ⅲ did not change significantly in DM LVH-I group compared with the EH LVH-I group; the CVF(4.23％ ± 0.69％) and CVF-Ⅰ (3.92％ ±0.40％) were decreased significantly(P ＜0.01); but CVF-Ⅲ(1.79％ ±0.21％) and Ⅰ/Ⅲ (2.20 ±0.20) did not change significantly in DM LVH-Ⅰ group compared with the EH LVH-Ⅰ group.Conclusions (1)The myocardial stiffness and the reduction of cardiac diastolic function deteriorated most with the development of LVH.(2)Under the condition of the same stage,the myocardial stiffness and the reduction of cardiac diastolic function deteriorated seriously in EH groups,diabetes patients,myocardial stiffness and the reduction of cardiac diastolic function deteriorated slightly.