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Journal of Southern Medical University ; (12): 1626-1627, 2010.
Artigo em Chinês | WPRIM | ID: wpr-336122

RESUMO

<p><b>OBJECTIVE</b>To observe the differences in the cytokine levels in the serum and ascites caused by Gram-positive or Gram-negative bacterial infection in patients with multiple organ dysfunction syndrome (MODS).</p><p><b>METHODS</b>The cytokines in the serum and ascites of the patients were examined by enzyme-linked immunosorbent assay in 27 patients with MODS due to Gram-positive (n=13) or Gram-negative (n=14) bacterial infection at day 1.</p><p><b>RESULTS</b>The levels of LPS and TNF-a were higher in the patients with Gram-negative bacterial infection than in patients with Gram-positive infection (P<0.05), but the levels of IL-6, IL-8 and IL-10 remained comparable between the two groups (P>0.05).</p><p><b>CONCLUSION</b>Testing of LPS and TNF-a in the serum and ascites of patients with MODS caused by Gram-positive or -negative bacterial infection may help to identify the pathogens for peritonitis resulting in MODS.</p>


Assuntos
Humanos , Ascite , Metabolismo , Infecções por Bactérias Gram-Negativas , Sangue , Metabolismo , Infecções por Bactérias Gram-Positivas , Sangue , Metabolismo , Interleucina-10 , Sangue , Metabolismo , Interleucina-6 , Sangue , Metabolismo , Interleucina-8 , Sangue , Metabolismo , Insuficiência de Múltiplos Órgãos , Sangue , Metabolismo , Microbiologia , Soro , Metabolismo , Fator de Necrose Tumoral alfa , Sangue , Metabolismo
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