RESUMO
The aim of the present research was to assess plasma selenium concentrations in healthy individuals, in the State of Mato Grosso do Sul, Brazil, as part of the mapping of the Brazilians states. Selenium levels were measured in 342 healthy individuals, using Inductively Coupled Plasma Spectrometry (ICP-OES). The average plasma selenium concentration in this study was 65±20 μg/L (mean±SD; range 21– 144 μg/L), the lowest in comparison to other Brazilian states. The predictor variables, such as gender, ethnicity, blood type or body mass index do not correlate with plasma selenium concentration.
RESUMO
PURPOSE:To evaluate the effect of ischemic postconditioning(IPC) on intestinal mucosa of rats subjected to ischemia and reperfusion process comparing two cycles of reperfusion and ischemia lasting two minutes each and four cycles of reperfusion and ischemia lasting 30 seconds eachMETHODS: Thirty Wistar rats were distributed into three groups: group A (10 rats), ischemia (30 minutes) and reperfusion (60 minutes); group B (10 rats), ischemia and reperfusion plus IPC by two lasting two minutes each; and Group C (10 rats), ischemia and reperfusion plus IPC by four cycles lasting 30 seconds each. Finally, a segment of small intestine was resected for histological analysis. We analysed the results according to Chiu et al. classification and proceeded to the statistical treatment by Kruskal-Wallis test (p<0.05).RESULTS: The mean degree of tissue injury according to Chiu et al. classification were: Group A, 2.77; in group B, 1.4; and group C, 1.4. B X C (p<0.05).CONCLUSIONS: Ischemic postconditioning was able to minimize reperfusion injury of rats undergone mesenteric ischemia and reperfusion process. There was no difference in the effectiveness of the method comparing two cycles of two minutes with four cycles of 30 seconds by H&E histological evaluation of the ileum after 60-minute reperfusion.