Levantamento de seio maxilar utilizando osso liofilizado associado a PRF ­ relato de caso / Maxillary sinus lift using lyophilized bone associated with PRF ­ case report

Para a reabilitação de espaços edêntulos, o tratamento de escolha na maioria dos casos é a reabilitação com implantes, mas nem sempre é possível executar esse tratamento devido às limitações anatômicas como, por exemplo, a reabsorção óssea que pode ocorrer após a extração dos dentes. Isso leva à utilização de técnicas de enxerto ósseo, sendo que nesse procedimento podem ser utilizados osso autógeno, biomateriais ou a associação de ambos. Os avanços clínicos, com a utilização de substitutos ósseos alógenos, xenógenos e aloplásticos, levam a considerar essas opções como válidas para o processo de reparo tecidual, devido à ausência de reabsorção em volume, ao sítio cirúrgico unitário e ao melhor pós-operatório. Visando acelerar a neoformação óssea, tem sido pesquisada a influência de células sanguíneas em biomateriais aplicados no corpo humano, como o de plasma rico em plaquetas (PRP), seguido da segunda geração de agregados de plaquetas, fibrina rica em plaquetas (PRFf). O PRF é constituído em medula óssea de megacariócitos (grande núcleo celular), plaquetas são estruturas discoidais e anucleares. Tem uma vida útil de 8 a 10 dias e o citoplasma contém muitos grânulos, cujos conteúdos são secretados no momento da ativação, α-grânulos contêm muitas proteínas, específicas de plaquetas ou não específicas de plaquetas. Contudo, desgranulação também implica a liberação de citocinas capazes de estimular a migração e proliferação de células no interior da matriz de fibrina, lançando as primeiras fases de cicatrização.

For rehabilitation of edentulous spaces rehabilitation, the treatment of choice in most cases is the rehabilitation with dental implants. however that approach is not always possible to perform due to anatomical limitations such as bone reabsorption after tooth extraction. Such cases require bone grafting techniques that may be performed using autogenous bone, biomaterials or a combination of both. Clinical improvements with the use of allogeneic, xenogenous and alloplastic bone substitutes indicate that those are valid options for the tissue repair process due to lack of volume reabsorption, the surgical site unit and the best postoperative results. To accelerate bone formation, it has been investigated the influence of blood cells on biomaterials applied to the human body, such as platelet-rich plasma (PRP), followed by the second generation of platelet aggregates, platelet-rich fibrin (PRF). The PRF consists of megakaryocytes bone marrow (large cell nucleus), platelets are discoidal and anuclear structures. It has a life span of 8 to 10 days, and the cytoplasm contains many granules which contents are secreted at the time of activation, α-granules contain many specific or non specific platelets proteins. however, degranulation also the releases of involves which are able to stimulate the migration and proliferation of cells within the fibrin matrix, releasing the early stages of cicatrization.

Evaluation of dry needling and 0.5% lidocaine injection therapies in myofascial pain trigger points in masticatory muscles

OBJECTIVE: The purpose of this study was to compare the effectiveness of trigger points injections using lidocaine 0.5% and dry needling without any kind of home-based rehabilitation program. METHODS: Sixteen patients with myofascial pain and trigger points in masticatory muscles were randomly assigned to two groups and received only one application session. The pressure pain threshold (PPT) was recorded before and after the injection: Ten minutes, 24 hours later, 7, 15, 21 and 30 days after the treatment. Visual analogue scale (VAS) was used to in all evaluation periods. RESULTS: There were no difference between groups for PPT, but for all groups the PPT during the time significantly increased when compared the before treatment. VAS showed differences between groups and during the time. The 0.5% lidocaine had the lowest VAS values when compared to dry needling, but at 30 days there were no differences among them. CONCLUSIONS: Despite the differences in VAS and considering there were no differences in PPT increases, we concluded that, in this study, both groups were able to disrupt the mechanisms of trigger point and relieve the myofascial pain symptoms.

Effect of experimental chewing on masticatory muscle pain onset

OBJECTIVES: To evaluate the effect of a chewing exercise on pain intensity and pressure-pain threshold in patients with myofascial pain. METHODS: Twenty-nine consecutive women diagnosed with myofascial pain (MFP) according to the Research Diagnostic Criteria comprised the experimental group and 15 healthy age-matched female were used as controls. Subjects were asked to chew a gum stick for 9 min and to stay at rest for another 9 min afterwards. Pain intensity was rated on a visual analog scale (VAS) every 3 min. At 0, 9 and 18 min, the pressure-pain threshold (PPT) was measured bilaterally on the masseter and the anterior, medium, and posterior temporalis muscles. RESULTS: Patients with myofascial pain reported increase (76 percent) and no change (24 percent) on the pain intensity measured with the VAS. A reduction of the PPT at all muscular sites after the exercise and a non-significant recovery after rest were also observed. CONCLUSION: The following conclusions can be drawn: 1. there are at least two subtypes of patients with myofascial pain that respond differently to experimental chewing; 2. the chewing protocol had an adequate discriminative ability in distinguishing patients with myofascial pain from healthy controls.

Quantidade de pressão e padrão de dor referida em pacientes portadores de dor miofascial / Pressure pain treshold and referred pain pattern in myofascial pain patients

Os propósitos deste estudo foram: determinar a quantidade de pressão que estimulasse resposta dolorosaem pacientes com pontos gatilho (PG) quando comparado ao grupo controle assintomático; determinar umintervalo de tempo de manutenção de pressão para que houvesse o surgimento do processo de dor referida(DR) e verificar o padrão de DR provocada. Selecionou-se 24 pacientes portadores de dor miofascial e parao grupo controle, 20 indivíduos livres de qualquer sintomatologia de disfunção temporomandibular. Ambos os grupos foram examinados por um único examinador em pontos gatilho previamente diagnosticados. Noitem quantidade de pressão, o intervalo no grupo portador de dor miofascial foi significantemente menor queo grupo controle. O padrão de DR obtido confere com aquele descrito na literatura. Os autores deste estudoconcluíram que o limiar de dor a palpação em portadores de dor miofascial é menor que em indivíduos nãoportadores e o padrão da manifestação de DR semelhante ao descrito na literatura.

The purposes of this study were: to determine the amount of pressure necessary to create painful responsein patients with myofascial pain in head and neck when compared with a assintomatic control group; to determineone sustained pressure time that causes referred pain and to determine the referred pain pattern whenthe trigger points were stimulated. The group A was formed by 24 patients who had myofascial pain, andgroup B was composed by 20 myofascial pain free subjects. For both groups, examination was performed byonly an experienced and trained professional. Group A had lower pressure pain threshold when comparedwith group B.( p < 0,01) The referred pain patterns was very similar to those described in literature. It wasconcluded that the pressure pain threshold in myofascial pain patients is lower than pressure pain thresholdin non-patients.