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Positron emission tomography [PET] has been utilized in numerous aspects of medicine since its introduction and development in 1970s. There has been a rapid improvement in imaging techniques and radiotracers in the last decade, which have enhanced the quality of PET in different biomedical research domains and patient care settings. In this editorial we will discuss applications of PET-computed tomography [CT]/magnetic resonance imaging [MRI] as well as other radiotracers in different variety of malignant and non-malignant diseases such as cardiovascular, central nervous system, inflammatory and systemic diseases and review new concepts applicable to this imaging modality
RESUMO
Neuroimaging techniques in audiovisual speech processing are innovative approach to neuroscience investigation that steadily influences the deep survey of highly mechanisms involved in this process. The purpose of this study was to evaluate brain activity via functional magnetic resonance imaging throughout audiovisual speech perception in Persian language. Functional MRI was used to assess 19 normal 20-30 year old women while they had been presented syllable /ka/ visually and /pa/ auditory using block design method, in which it would provide two series of imaging, functional and T1-weighted. Subsequently, the results were analyzed and compared by FSL software. The results of this study pointed out that both middle and cortical regions of brain are activated in visual stimuli and its middle regions are activated in response to auditory stimuli. Hence, left anterior supramarginal, some parts of motor speech system including insular and cingulated cortex-precentral cortex were stimulated with visual stimulus and left posterior supramarginal as well as right supramarginal gyrus were stimulated with auditory stimulus. Moreover, in this investigation, McGurk effect was behaviorally proven in fifteen subjects. It was hypothesized that the activation of unique region, supramarginal gyrus, with both audio and visual stimuli indicated the presence of commonplace region for phonologic processing of sensory inputs. In addition, auditory stimuli develop more intense activity; and on the other hand, broaden-maximum voxel-as well as extra regions are demonstrated in response to visual stimuli. These points represent the unfamiliarity of normal individual brain to percept visual speech stimuli