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1.
Indian J Exp Biol ; 1998 Mar; 36(3): 237-44
Artigo em Inglês | IMSEAR | ID: sea-60938

RESUMO

Bone morphogenetic proteins (BMPs), hydrophobic, non-species specific glycoproteins, belong to the expanding transforming growth factor-beta (TGF-beta) superfamily. BMP has pleiotropic function that range from extraskeletal and skeletal organogenesis to bone generation and regeneration. It induces de novo bone formation in post fetal life through the process of direct (intra membranous) and endochondral ossification and their response is dose dependent. Through recombinant gene technology, BMP is available at least in ten forms for basic research and clinical trials. Amino acid sequences and physical properties of BMP family members have been identified. BMP research extends to the fields of developmental biology, genetics and evolution.


Assuntos
Adulto , Sequência de Aminoácidos , Animais , Desenvolvimento Ósseo/fisiologia , Proteínas Morfogenéticas Ósseas/química , Criança , Humanos , Dados de Sequência Molecular
4.
Indian Pediatr ; 1992 Mar; 29(3): 343-9
Artigo em Inglês | IMSEAR | ID: sea-12438
5.
Indian Pediatr ; 1990 Dec; 27(12): 1303-5
Artigo em Inglês | IMSEAR | ID: sea-12822
6.
Indian Pediatr ; 1990 Sep; 27(9): 978-80
Artigo em Inglês | IMSEAR | ID: sea-7211
7.
Indian Pediatr ; 1989 Sep; 26(9): 875-81
Artigo em Inglês | IMSEAR | ID: sea-11759

RESUMO

Forty-six malnourished children between 3-48 mo with varying grades of malnutrition (PEM) were evaluated for left ventricular function by echocardiography. None of these children had any pre-existing cardiac disease, chronic illness or significant anemia. Children with Grades III and IV PEM had significantly smaller cardiac chamber size and ventricular wall thickness as compared to normally nourished children. Cardiac output as well as other indices of left ventricular function (percentage fractional shortening, mean rate of circumferential fibre shortening and ejection fraction) were also significantly decreased in severe PEM. The atrophic PEM heart does appear to show left ventricular dysfunction in moderately severe malnutrition.


Assuntos
Volume Cardíaco/fisiologia , Ecocardiografia , Ecocardiografia Doppler , Ventrículos do Coração/fisiopatologia , Hemodinâmica/fisiologia , Humanos , Lactente , Contração Miocárdica/fisiologia , Desnutrição Proteico-Calórica/fisiopatologia
8.
Indian Pediatr ; 1989 Jun; 26(6): 577-9
Artigo em Inglês | IMSEAR | ID: sea-6244
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