RESUMO
Background: Chronic obstructive pulmonary disease (COPD) is a growing cause of morbidity and mortality worldwide Abnormalities in thyroid hormone regulation are encountered frequently in nonthyroidal diseases. Hence; the present study was undertaken for assessing the correlation of thyroid hormone among COPD patients. Materials & Methods: In the present study, a total of 200 patients were enrolled, which were diagnosed to be suffering from COPD. Complete medical history and family history of all the subjects was also obtained. Blood samples were taken from all the patients and were sent to laboratory for assessment of thyroid profile. COPD patients were divided into four stages as follows: Stage 1- Mild, Stage 2- Moderate, Stage 3- Severe, and Stage 4- Very Severe. All the results were recorded in Microsoft excel sheet and were analyzed by SPSS software. Results: Thyroid dysfunction was found to be present in 47 patients (23.5 percent of patients). Among 200 COPD patients, 52, 45, 50 and 53 patients were of stage 1, 2, 3 and 4 respectively. Among 53 patients of stage 4, thyroid dysfunction was found to be present in 33.96 percent of the patients. Among 50 patients of stage 3, thyroid dysfunction was found to be present in 24 percent of the patients. Among 45 patients of stage 2, thyroid dysfunction was found to be present in 20 percent of the patients. Among 52 patients of stage 1, thyroid dysfunction was found to be present in 15.38 percent of the patients. Conclusion: Thyroid dysfunction is a serious health problem affecting more commonly in patients with stage 3 and stage 4 COPD.