Clinical, Cytological and Histopathological Study of Salivary Gland Lesions

Background: A prospective study was conducted in the Department of Pathology, GMC Patiala for two years on 60 patients with swellings of jaw seeking consultation in Rajindra Hospital, Patiala. Methods: Fine Needle Aspiration Cytology (FNAC) was done on all these patients followed by microscopic examination of the prepared slides and relevant clinical information was collected. The data was compiled and analysed statistically. In lesions where surgery followed FNAC, the comparison was done with histopathology and statistical values were calculated. Results: The results of the study were: non-neoplastic cases were 51.7% and neoplastic cases were 48.3%. Maximum cases were of chronic sialadenitis (30%) followed by pleomorphic adenoma (23.3%). Parotid gland was involved in maximum cases (60%). Biopsies or specimens for histopathological examination were received for 30 cases; maximum cases of which were diagnosed as pleomorphic adenoma on histopathology. Among malignant tumors, mucoepidermoid carcinoma was the most common. Conclusion: On correlating the cytological and histopathological nature of salivary gland lesions, sensitivity of FNAC came out to be 75%, specificity 100% and accuracy was calculated as 93.3%.

Histopathological Correlation of Adenomyosis, Leiomyoma and Dual Pathology in Hysterectomy Specimens as the Cause of Abnormal Uterine Bleeding In Women in Different Age Groups

Background: The objective was to study adenomyosis and leiomyoma as the cause of abnormal uterine bleeding in hysterectomy specimens. Methods: This was a study carried out on 100 hysterectomy specimens, of subjects who presented to the department of Obstetrics and Gynaecology at Government Medical College, Patiala with the complaint of abnormal uterine bleeding. Data including age, parity, symptoms and clinical indication for hysterectomy was collected for the study and the histopathological findings were recorded. The specimens were well grossed and stained with hematoxylin and eosin and examined microscopically.Results: Women in the perimenopausal age (41-50 years) accounted for the highest number of cases (35, 44.30%) presenting with symptoms of AUB. In this age group leiomyoma was found to be the commonest cause of AUB (19, 54.28%). The most common symptom was heavy menstrual bleeding. Clinical, radiological and pathological evaluation correlated well with the diagnosis of leiomyoma but was of little help in diagnosing adenomyosis. Conclusion: Hence, adenomyosis still remains a clinical challenge and should be kept in mind by the clinician as well as the pathologist in women presenting with AUB.