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Indian J Exp Biol ; 1990 Jan; 28(1): 10-7
Artigo em Inglês | IMSEAR | ID: sea-59667

RESUMO

In this study initially a precancerous condition, leukoplakia, was develop at 6 weeks treatment of DMBA whereas in the animals treated both DMBA + Vit. A, leukoplakia was seen at 10 weeks followed by papilloma or nodules at 12 weeks. Tumours induced by DMBA were more in number than DMBA + Vit. A treated tumours. The histological and ultrastructural changes were enhanced and prominent in DMBA treated animals at 12 weeks, where as these changes were considerably less in animals treated with DMBA + vit. A at 12 weeks.


Assuntos
9,10-Dimetil-1,2-benzantraceno/toxicidade , Animais , Cricetinae , Feminino , Leucoplasia Oral/induzido quimicamente , Masculino , Mesocricetus , Microscopia Eletrônica , Neoplasias Bucais/induzido quimicamente , Papiloma/induzido quimicamente , Vitamina A/farmacologia
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