fNIRS Assessment during an Emotional Stroop Task among Patients with Depression: Replication and Extension

OBJECTIVE: Accumulated evidence collected via functional near-infrared spectroscopy (fNIRS) has been reported with regard to mental disorders. A previous finding revealed that emotional words evoke left frontal cortex activity in patients with depression. The primary aim of the current study was to replicate this finding using an independent dataset and evaluate the brain region associated with the severity of depression using an emotional Stroop task. METHODS: Oxygenized and deoxygenized hemoglobin recording in the brain by fNIRS on 14 MDD patients and 20 normal controls. RESULTS: Hyperactivated oxygenized hemoglobin was observed in the left frontal cortex on exposure to unfavorable stimuli, but no significant difference was found among patients with depression compared with healthy controls on exposure to favorable stimuli. This result is consistent with previous findings. Moreover, an evoked wave associated with the left upper frontal cortex on favorable stimuli was inversely correlated with the severity of depression. CONCLUSION: Our current work using fNIRS provides a potential clue regarding the location of depression symptom severity in the left upper frontal cortex. Future studies should verify our findings and expand them into a precise etiology of depression.

Effects of Work-Related Factors and Work-Family Conflict on Depression among Japanese Working Women Living with Young Children

Objective: In a Japanese metropolis, we examined the effects of work-related factors and work-family conflict on depressive symptoms among working women living with young children. Methods: Data was derived from women (n=501) who lived with at least one preschool child and worked for 20 hours or more per week. As work-related factors, we chose job pressure, skill underutilization, dissatisfaction with personal income, inflexible work schedule, job insecurity, and relationships in the workplace. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale. The effects of work-related factors and work-family conflict on depressive symptoms were explored by hierarchical regression analysis. Results: Work-related factors except job pressure were significantly correlated with depressive symptoms. Multiple regression analyses revealed that women who had more frequent work-family conflict and more work-related stressors such as bad relationships in the workplace, job insecurity, and underutilization of skills were likely to have more depressive symptoms. Conclusions: Among women workers with young children, work-family conflict and various work-related factors such as perceived bad relationships at work, job insecurity, and underutilization of skills had a significant relationship with depressive symptoms. Much more research is needed to explore ways to support working mothers.

Effects of work-related factors and work-family conflict on depression among Japanese working women living with young children

<p><b>OBJECTIVE</b>In a Japanese metropolis, we examined the effects of work-related factors and work-family conflict on depressive symptoms among working women living with young children.</p><p><b>METHODS</b>Data was derived from women (n=501) who lived with at least one preschool child and worked for 20 hours or more per week. As work-related factors, we chose job pressure, skill underutilization, dissatisfaction with personal income, inflexible work schedule, job insecurity, and relationships in the workplace. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale. The effects of work-related factors and work-family conflict on depressive symptoms were explored by hierarchical regression analysis.</p><p><b>RESULTS</b>Work-related factors except job pressure were significantly correlated with depressive symptoms. Multiple regression analyses revealed that women who had more frequent work-family conflict and more work-related stressors such as bad relationships in the workplace, job insecurity, and underutilization of skills were likely to have more depressive symptoms.</p><p><b>CONCLUSIONS</b>Among women workers with young children, work-family conflict and various work-related factors such as perceived bad relationships at work, job insecurity, and underutilization of skills had a significant relationship with depressive symptoms. Much more research is needed to explore ways to support working mothers.</p>

Increasing obesity among male workers in Japan: 1992-1997

<p><b>OBJECTIVE</b>To examine changes in the Body Mass Index (BMI) and in the prevalence of obesity among male Japanese workers after five years.</p><p><b>DESIGN</b>Follow-up study, based on data from annual health checkups performed at workplaces.</p><p><b>SUBJECTS AND METHODS</b>We had access to the data for a total of 63,951 male workers aged 20 through 54 years in 1992 who were examined in both 1992 and 1997. In quinquennial cohorts, we compared the findings for mean BMI and the prevalence of obesity in 1992 with the findings in 1997.</p><p><b>RESULTS</b>Between 1992 and 1997, in all cohorts the mean BMI increased significantly. For each adjacent cohort pair the mean BMI value in 1997 was significantly higher than in 1992. In 1992, 21.3% of all subjects were obese, increasing by 3.4% after five years to 24.7% in 1997. In the younger 1968-1972 and 1963-1967 cohorts the prevalence of obesity increased by 6.3% during five years. The significant increase in the obesity prevalence was observed from 1992 to 1997 for each age-adjusted cohort.</p><p><b>CONCLUSIONS</b>These results suggest a substantial increase in obesity among male Japanese workers. The notable increase in the prevalence of obesity among young male adults and the general trend toward widespread obesity during five years signal an increasing risk of lifestyle-related diseases.</p>

Increasing Obesity among Male Workers in Japan: 1992-1997

Objective: To examine changes in the Body Mass Index (BMI) and in the prevalence of obesity among male Japanese workers after five years. Design: Follow-up study, based on data from annual health checkups performed at workplaces. Subjects and Methods: We had access to the data for a total of 63,951 male workers aged 20 through 54 years in 1992 who were examined in both 1992 and 1997. In quinquennial cohorts, we compared the findings for mean BMI and the prevalence of obesity in 1992 with the findings in 1997. Results: Between 1992 and 1997, in all cohorts the mean BMI increased significantly. For each adjacent cohort pair the mean BMI value in 1997 was significantly higher than in 1992. In 1992, 21.3% of all subjects were obese, increasing by 3.4% after five years to 24.7% in 1997. In the younger 1968—1972 and 1963—1967 cohorts the prevalence of obesity increased by 6.3% during five years. The significant increase in the obesity prevalence was observed from 1992 to 1997 for each age-adjusted cohort. Conclusions: These results suggest a substantial increase in obesity among male Japanese workers. The notable increase in the prevalence of obesity among young male adults and the general trend toward widespread obesity during five years signal an increasing risk of lifestyle-related diseases.

Seismic Intensity and Mental Stress after the Great Hanshin-Awaji Earthquake

Objective: For 1,361 victims of the Great Hanshin-Awaji Earthquake, to evaluate the usefulness of seismic intensity information for mental health activities, we examined the quantitative relationship between experienced seismic intensity and earthquake-related life events or mental health. Methods: Questionnaires were administered concerning seismic intensity, life events and mental health to the victims. Results: The incidence of serious life events, such as death of a close family member and mental disorders were higher in areas of high seismic intensity than in low-intensity areas. Victims who experienced intensity 7 (Japan Meteorological Agency) scored 11 or more on the Modified Mercalli (MM) scale, perceived more depressive symptoms [odds ratio (OR) 2.11, 95% confidence interval (95% CI), 1.49−2.98)] and lower mental health status (OR 1.87, 95% CI 1.34−2.61) than those who suffered intensity 4 or less, who scored 7 or less on MM scale after controlling for various sociodemographic factors. Conclusions: Higher seismic intensity was associated with each severe life event and ill mental health among earthquake victims.

Life Events and Posttraumatic Stress in Hanshin-Awaji Earthquake Victims

Stress induced by disaster is experienced to varying degrees by all respondents, and is known to evoke psychophysiological reactions. In this study, we investigated the relationships between earthquake-related life events and posttraumatic stress symptoms. A total of 380 adults were surveyed one year after the 1995 Hanshin-Awaji earthquake in Japan. The questionnaire included items concerning earthquake-related life events, emotional support and posttraumatic stress disorder (PTSD) symptoms. As a result, after controlling for demographic variables, earthquake-related life events were significantly related to the grade of posttraumatic stress and its three components: re-experience, avoidance and arousal, in both male and female subjects. Male subjects who currently had lower emotional support showed higher scores of posttraumatic stress and arousal. In conclusion, a higher experience of earthquake-related life events appears to be an important risk factor for development of poor mental health status following an earthquake disaster.

The Relationship of Lifestyle Factors, Personal Character, and Mental Health Status of Employees of a Major Japanese Electrical Manufacturer

To examine the relationship lifestyle factors, personal character, mental health status, and job strain a self-administered questionnaire survey was conducted among employees of a leading electrical manufacturing company in Japan. A total of 2, 327 workers (Male=1, 668, Female=659) responded to the survey. We analyzed the relationships of health practices based on such factors as: Free child (FC) from the Egogram, the Working-life satisfaction, and the General Health Questionnaire-28 through Path-analysis techniques.The following results were obtained: The mental health status was significantly affected by such factors as health practices, Working-life satisfaction, personal character (FC), life satisfaction, and age. Health practices and personal character (FC) showed a direct relationship to the mental health status and an indirect relationship to the Working-life satisfaction and life satisfaction. The variances accounting for mental health status were 41.8% in male workers and 43.8% in female workers.Path-analysis data suggested that mental health status was affected about 40% by lifestyle, personal character, Working-life satisfaction, and life satisfaction. It was suggested that there might be important factors affecting mental health status but which are unknown to us by as much as 60% in the present day. These findings suggested the necessity of further investigation of the relationship among lifestyle factors, mental health status, and job strain among employees of a reputable company in the present day.