Prenatal onset infantile cortical hyperostosis [caffey disease]: an Egyptian report

Prenatal onset infantile cortical hyperostosis [prenatal form of Caffey disease] is an uncommon disease characterized by polyhydramnios, pulmonary hypoplasia, hepatomegaly, bowed hyperostotic long bones, and a poor prognosis [1]. We report a fetus of 33 weeks of gestation whose clinical and radiological findings are compatible with the severe form of this disease. The occurrence of this form in two siblings provides further evidence for the recessive form of inheritance