effects of three sessions of running on a negative slope on serum levels of liver enzymes in adult male rats

The purpose of this study was to investigate the effects of three sessions of running on a negative slope [eccentric contraction] on changes of the serum levels of aspartate aminotransferase [AST] and alanin aminotransferaze [ALT] in adult male rats. 20 adult male rats were divided randomly into two equal groups [exercise and control]. Levels of AST and ALT in both groups were measured in a fasting state, 24 hours before and 24 hours after the last session of training. Exercise increased the levels of serum AST and ALT enzymes, significantly [p<0.05]. Eccentric exercise, without allowing enough time for returning to the pre-exercise state, leads to the damage of some body organs such as the liver