RESUMO
Serum Procalcitonin(PCT) has become useful as a biomarker to assist in the diagnosis of sepsis, as well as related infectious or in?ammatory conditions. It is a soluble protein liberated into the circulation of patients in response to severe systemic in?ammation, in particular by bacterial infection. The aim of this study was to evaluate the usefulness of Procalcitonin as a biomarker of sepsis in the early strati?cation of adult patients admitted to the intensive care unit with suspected infection.Patients are randomly divided into two groups , Group-1: comprising those patients with a bacterial infection (SIRS with Sepsis) and Group -2: comprising patients without a bacterial infection (SIRS without Sepsis). we found that elevated PCT concentrations (> 0.5ng/ml) were detected in a signi?cantly higher proportion of patients with SIRS with sepsis compared to those with SIRS without sepsis so we concluded that PCT is an excellent marker providing the additive effect to improve the predictive power for diagnosing sepsis, for assessing severity of sepsis, and also for predicting the outcome/prognosis.