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1.
Journal of Korean Medical Science ; : e239-2023.
Artigo em Inglês | WPRIM | ID: wpr-1001056

RESUMO

Background@#Large-scale studies about epidemiologic characteristics of renal infarction (RI) are few. In this study, we aimed to analyze the incidence and prevalence of RI with comorbidities in the South Korean population. @*Methods@#We investigated the medical history of the entire South Korean adult population between 2013 and 2019 using the National Health Insurance Service database (n = 51,849,591 in 2019). Diagnosis of RI comorbidities were confirmed with International Classification of Disease, Tenth Revision, Clinical Modification codes. Epidemiologic characteristics, distribution of comorbidities according to etiologic mechanisms, and trend of antithrombotic agents were estimated. @*Results@#During the 7-years, 10,496 patients were newly diagnosed with RI. The incidence rate increased from 2.68 to 3.06 per 100,000 person-years during the study period.The incidence rate of RI increased with age peaking in the 70s with 1.41 times male predominance. The most common comorbidity was hypertension, followed by dyslipidemia and diabetes mellitus. Regarding etiologic risk factor distribution, high embolic risk group, renovascular disease group, and hypercoagulable state group accounted for 16.6%, 29.1%, and 13.7% on average, respectively. For the antithrombotic treatment of RI, the prescription of antiplatelet agent gradually decreased from 17.0% to 13.0% while that of anticoagulation agent was maintained around 35%. The proportion of non-vitamin K antagonist oral anticoagulants remarkably increased from only 1.4% to 17.6%. @*Conclusion@#Considering the progressively increasing incidence of RI and high prevalence of coexisting risk factors, constant efforts to raise awareness of the disease are necessary. The current epidemiologic investigation of RI would be the stepping-stone to establishing future studies about clinical outcomes and optimal treatment strategies.

2.
Journal of Korean Academy of Fundamental Nursing ; : 1-12, 2023.
Artigo em Coreano | WPRIM | ID: wpr-968938

RESUMO

Purpose@#The purpose of this study was to investigate factors affecting quality of life in hemodialysis patients. @*Methods@#In this descriptive study, the subjects were 127 hemodialysis patients at four dialysis clinics in Pusan and Daegu metropolitan cities. Data were analyzed with descriptive statistics, independent t-test, one-way analysis of variance, Pearson’s correlation coefficients, and stepwise multiple regression analysis using SPSS/WIN version 26.0. @*Results@#The average scores for social support, symptom experience, physical function, self-care compliance, and quality of life were 3.97±0.66, 38.50±27.94, 2.24±0.60, 3.43±0.49, and 3.02±0.57, respectively. Fifty-five (43.3%) subjects had a type D personality. Quality of life showed significant differences according to educational background (F=6.44, p<.001), job (t=2.52, p=.013), and type D personality (t=4.39, p<.001). Social support (r=.32, p<.001), physical function (r=.45, p<.001), self-care compliance (r=.24, p=.005), albumin (r=.09, p=.027), and phosphorous (r=.27, p=.002) were positively correlated with quality of life. Symptom experience (r=-.40, p<.001) was negatively correlated with quality of life. The factors affecting quality of life were social support (β=.31, p<.001), physical function (β=.30, p<.001), educational background (β=.20, p=.007), type D personality (β=-.19, p<.001), and symptom experience (β=-.18, p=.019), with a total explanatory power of approximately 43%. @*Conclusion@#Quality of life in hemodialysis patients was affected by social support, physical function, educational background, type D personality, and symptom experience. These factors should be considered in nursing interventions to improve quality of life of hemodialysis patients.

3.
Journal of Korean Clinical Nursing Research ; (3): 233-244, 2021.
Artigo em Inglês | WPRIM | ID: wpr-915340

RESUMO

Purpose@#The purpose of this study was to investigate the actual utilization of clinical practice guidelines developed by Hospital Nurses Association. @*Methods@#The subjects were 70 nurses who were in charge of guideline distributions in 70 advanced general hospital and general hospitals with 500 beds or more nationwide.Data were collected between June and August, 2020 by mail (return rate: 88.6%). Data were analyzed using descriptive statistics, t-test, and ANOVA with SPSS/WIN 24.0. @*Results@#Among the clinical practice guidelines developed by Hospital Nurses Association, 72.9~90.1% were placed with book and electronic file in nursing department and 24.3~35.8% were placed with book and electronic file in each nursing unit at hospital. The average number of utilized clinical practice guidelines were 3.96±3.88, and average score of guideline utilization was score 2.85±0.79 which means ‘use sometimes’. @*Conclusion@#To improve the distribution and utilization of the clinical practice guidelines, it is necessary to enhance the recognition of values of evidence based nursing practice targeting head of nursing department and to stimulate the distribution and utilization of the clinical practice guidelines using diverse education programs for staff nurses.

4.
Obstetrics & Gynecology Science ; : 543-547, 2020.
Artigo em Inglês | WPRIM | ID: wpr-902908

RESUMO

A 39-year-old nulliparous woman experienced continuous mild fever and abdominal pain since undergoing laparoscopic ovarian dermoid cystectomy 3 months previously in a local hospital. Abdominal computed tomography revealed diffuse heterogeneous fat infiltrations with numerous micronodules in the greater and lesser omentum, combined with ascites with thickening of the parietal peritoneum. The patient underwent exploratory laparoscopy, which included partial pelvic peritonectomy, excision of granulomas, and adhesiolysis with massive irrigation. The patient was treated successfully with laparoscopic surgery and all reproductive structures were spared without operative complications. To avoid peritonitis, complete removal of cyst contents and massive irrigation should be performed during ovarian dermoid cystectomy. Conservative surgical treatment may be a good choice for treating granulomatous peritonitis induced by iatrogenic rupture.

5.
The Korean Journal of Thoracic and Cardiovascular Surgery ; : 277-284, 2020.
Artigo | WPRIM | ID: wpr-835303

RESUMO

Background@#Cardiac arrest during or after office-based cosmetic surgery is rare, and little is known about its prognosis. We assessed the clinical outcomes of patients who developed cardiac arrest during or after cosmetic surgery at office-based clinics. @*Methods@#Between May 2009 and May 2016, 32 patients who developed cardiac arrest during or after treatment at cosmetic surgery clinics were consecutively enrolled. We compared clinical outcomes, including complications, between survivors (n=19) and non-survivors (n=13) and attempted to determine the prognostic factors of mortality. @*Results@#All 32 of the patients were female, with a mean age of 30.40±11.87 years. Of the 32 patients, 13 (41%) died. Extracorporeal life support (ECLS) was applied in a greater percentage of non-survivors than survivors (92.3% vs. 47.4%, respectively; p=0.009). The mean duration of in-hospital cardiopulmonary resuscitation (CPR) was longer for the non-survivors than the survivors (31.55±33 minutes vs. 7.59±9.07 minutes, respectively; p=0.01).The mean Acute Physiology and Chronic Health Evaluation score was also higher among non-survivors than survivors (23.85±6.68 vs. 16.79±7.44, respectively; p=0.01). No predictor of death was identified in the patients for whom ECLS was applied. Of the 19 survivors, 10 (52.6%) had hypoxic brain damage, and 1 (5.3%) had permanent lower leg ischemia.Logistic regression analyses revealed that the estimated glomerular filtration rate was a predictor of mortality. @*Conclusion@#Patients who developed cardiac arrest during or after cosmetic surgery at office-based clinics experienced poor prognoses, even though ECLS was applied in most cases. The survivors suffered serious complications. Careful monitoring of subjects and active CPR (when necessary) in cosmetic surgery clinics may be essential.

6.
Obstetrics & Gynecology Science ; : 543-547, 2020.
Artigo em Inglês | WPRIM | ID: wpr-895204

RESUMO

A 39-year-old nulliparous woman experienced continuous mild fever and abdominal pain since undergoing laparoscopic ovarian dermoid cystectomy 3 months previously in a local hospital. Abdominal computed tomography revealed diffuse heterogeneous fat infiltrations with numerous micronodules in the greater and lesser omentum, combined with ascites with thickening of the parietal peritoneum. The patient underwent exploratory laparoscopy, which included partial pelvic peritonectomy, excision of granulomas, and adhesiolysis with massive irrigation. The patient was treated successfully with laparoscopic surgery and all reproductive structures were spared without operative complications. To avoid peritonitis, complete removal of cyst contents and massive irrigation should be performed during ovarian dermoid cystectomy. Conservative surgical treatment may be a good choice for treating granulomatous peritonitis induced by iatrogenic rupture.

7.
Journal of Korean Medical Science ; : e25-2020.
Artigo em Inglês | WPRIM | ID: wpr-892091

RESUMO

BACKGROUND@#This study aimed to evaluate the association between baseline results of the Timed Up and Go (TUG) test and subsequent functional dependency occurrence.@*METHODS@#From the National Health Insurance Service-Senior Cohort database, we identified 39,519 people who participated in the National Screening Program for Transitional Ages at the age of 66 during 2007–2008. Impaired mobility was defined as taking 10 seconds or longer to perform the TUG test. Functional dependency occurrence was defined as the initiation of receiving national Long-Term Care Insurance services—home care or admission to long-term care facilities. Cox proportional hazard regression models were used to assess the hazard ratios (HRs) for dependency occurrence according to baseline TUG test results.@*RESULTS@#The mean follow-up period was 5.7 years. Occurrence rates of dependency were 2.0 and 3.4 cases per 1,000 person-years in the normal and impaired TUG groups, respectively. Impaired mobility was associated with a higher risk of functional dependency occurrence (adjusted HR [aHR], 1.65; 95% confidence interval [CI], 1.40–1.95; P < 0.001). Additionally, in the subgroup analysis for the participants with intact baseline activities of daily living, impaired mobility was associated with a higher risk of dependency occurrence (aHR, 1.65; 95% CI, 1.33–2.04; P < 0.001).@*CONCLUSION@#The TUG test might be a useful predictive marker of subsequent functional dependency occurrence. Intervention to prevent functional dependency may be helpful for older adults with impairment on the TUG test.

8.
Journal of Korean Clinical Nursing Research ; (3): 296-304, 2020.
Artigo em Inglês | WPRIM | ID: wpr-891919

RESUMO

Purpose@#This study was conducted to demonstrate objective stability of postoperative pain management status managed by nurse-based, anesthesiologist-supervised Acute Pain Service (APS). @*Methods@#A retrospective descriptive review was conducted with 5,748 patients who had used intravenous Patient Controlled Analgesia (PCA) from January to December 2017. Data were analyzed using descriptive statics, Frequency analysis, ANOVA, Cross tabulation with X2 test, and Correlation coefficient. @*Results@#As the APS nurse's education date increased, the period of using PCA was statistically significantly longer, and the period of stopping PCA while using it became shorter (p<.001). Statistically significant, the most painful operations were extremities, spine, upper abdomen, and thorax, while the least painful surgery was lower abdomen (p<.001). Lower abdominal surgery used the highest amount of PCA (p<.001), and extremities and spinal surgery, the lowest amount of PCA and frequently stop using it (p<.001). The most common side effects were nausea and vomiting after surgery, with an incidence of 16.0% within 24 hours and 9.8% within 48 hours. The overall error caused by PCA was 1.5%, with 84.3% being caused by human errors. @*Conclusion@#With the pain management effect of APS nurses, patients used PCA more effectively. There were also fewer side effects and error rates compared to prior studies.Therefore, it is suggested that this system is safe and effective for pain management.

9.
Journal of Korean Academy of Nursing ; : 116-131, 2020.
Artigo em Coreano | WPRIM | ID: wpr-891777

RESUMO

PURPOSE@#This study aimed to develop a smartphone overdependence prevention program for college students based on the self-determination theory (SDT) and evaluate its effectiveness.@*METHODS@#A non-equivalent control group repeated measures design was used for the study. Participants were 64 university freshmen (experimental group: 29, control group: 35). The developed program consists of eight sessions conducted twice a week. The program was designed to promote autonomy, competence, and relatedness the three elements of the basic psychological needs of self-determination theory. The participants were assessed before the program, immediately after, and 1 and 3 months after the program. Data were collected from April 23 to September 14, 2018 and analyzed by performing a Chi-square test, Fisher's exact test, independent t-test, and repeated measures ANOVA using SPSS/WIN 23.0.@*RESULTS@#This study showed improvement in the basic psychological needs (F=3.90, p =.010) in the experimental group compared to the control group. Specifically, competence (F=2.93, p =.035), relatedness (F=2.89, p =.045), and self-regulatory ability (F=3.11, p =.028) improved significantly.@*CONCLUSION@#Study findings indicate thatthe smartphone overdependence prevention program based on the Self-determination theory could be an effective intervention for improving basic psychological needs and self-regulation ability. Therefore, this program could be an efficient strategy for smartphone overdependence prevention in university students.

10.
Journal of Korean Academy of Nursing ; : 116-131, 2020.
Artigo em Coreano | WPRIM | ID: wpr-811224

RESUMO

PURPOSE: This study aimed to develop a smartphone overdependence prevention program for college students based on the self-determination theory (SDT) and evaluate its effectiveness.METHODS: A non-equivalent control group repeated measures design was used for the study. Participants were 64 university freshmen (experimental group: 29, control group: 35). The developed program consists of eight sessions conducted twice a week. The program was designed to promote autonomy, competence, and relatedness the three elements of the basic psychological needs of self-determination theory. The participants were assessed before the program, immediately after, and 1 and 3 months after the program. Data were collected from April 23 to September 14, 2018 and analyzed by performing a Chi-square test, Fisher's exact test, independent t-test, and repeated measures ANOVA using SPSS/WIN 23.0.RESULTS: This study showed improvement in the basic psychological needs (F=3.90, p =.010) in the experimental group compared to the control group. Specifically, competence (F=2.93, p =.035), relatedness (F=2.89, p =.045), and self-regulatory ability (F=3.11, p =.028) improved significantly.CONCLUSION: Study findings indicate thatthe smartphone overdependence prevention program based on the Self-determination theory could be an effective intervention for improving basic psychological needs and self-regulation ability. Therefore, this program could be an efficient strategy for smartphone overdependence prevention in university students.


Assuntos
Humanos , Competência Mental , Autonomia Pessoal , Autocontrole , Smartphone
12.
Journal of Korean Academy of Fundamental Nursing ; : 236-245, 2020.
Artigo em Coreano | WPRIM | ID: wpr-919727

RESUMO

Purpose@#The purpose of this study was to identify factors affecting preventive behavior related to tuberculosis (TB). The focus was on knowledge, attitude and optimistic bias related to tuberculosis among university students in Korea. @*Methods@#A descriptive cross-sectional study was conducted with 255 students from 6 universities in 6 regions in Korea. Data were collected using a structured questionnaire online. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation coefficients, and multiple linear regression. @*Results@#The level for scores on preventive behavior for TB was slightly good, knowledge related to TB was moderate, and attitude was good. There was a slight optimistic bias. Knowledge and attitude related to TB were positively correlated with preventive behavior for TB. The factors affecting preventive behavior for TB were attitude (β=.36,p<.001), knowledge related to TB (β=.13, p=.025). The explanatory power of these variables was 26.1% (F=10.98,p<.001). @*Conclusion@#Findings suggest that knowledge and attitude related to TB are major factors influencing preventive behavior for TB. In order to improve preventive behavior for TB, it is necessary to establish effective educational strategies and TB information media utilization that firmly enhance attitude and improve knowledge related to TB in university students in Korea.

13.
Journal of Korean Medical Science ; : e25-2020.
Artigo em Inglês | WPRIM | ID: wpr-899795

RESUMO

BACKGROUND@#This study aimed to evaluate the association between baseline results of the Timed Up and Go (TUG) test and subsequent functional dependency occurrence.@*METHODS@#From the National Health Insurance Service-Senior Cohort database, we identified 39,519 people who participated in the National Screening Program for Transitional Ages at the age of 66 during 2007–2008. Impaired mobility was defined as taking 10 seconds or longer to perform the TUG test. Functional dependency occurrence was defined as the initiation of receiving national Long-Term Care Insurance services—home care or admission to long-term care facilities. Cox proportional hazard regression models were used to assess the hazard ratios (HRs) for dependency occurrence according to baseline TUG test results.@*RESULTS@#The mean follow-up period was 5.7 years. Occurrence rates of dependency were 2.0 and 3.4 cases per 1,000 person-years in the normal and impaired TUG groups, respectively. Impaired mobility was associated with a higher risk of functional dependency occurrence (adjusted HR [aHR], 1.65; 95% confidence interval [CI], 1.40–1.95; P < 0.001). Additionally, in the subgroup analysis for the participants with intact baseline activities of daily living, impaired mobility was associated with a higher risk of dependency occurrence (aHR, 1.65; 95% CI, 1.33–2.04; P < 0.001).@*CONCLUSION@#The TUG test might be a useful predictive marker of subsequent functional dependency occurrence. Intervention to prevent functional dependency may be helpful for older adults with impairment on the TUG test.

14.
Journal of Korean Clinical Nursing Research ; (3): 296-304, 2020.
Artigo em Inglês | WPRIM | ID: wpr-899623

RESUMO

Purpose@#This study was conducted to demonstrate objective stability of postoperative pain management status managed by nurse-based, anesthesiologist-supervised Acute Pain Service (APS). @*Methods@#A retrospective descriptive review was conducted with 5,748 patients who had used intravenous Patient Controlled Analgesia (PCA) from January to December 2017. Data were analyzed using descriptive statics, Frequency analysis, ANOVA, Cross tabulation with X2 test, and Correlation coefficient. @*Results@#As the APS nurse's education date increased, the period of using PCA was statistically significantly longer, and the period of stopping PCA while using it became shorter (p<.001). Statistically significant, the most painful operations were extremities, spine, upper abdomen, and thorax, while the least painful surgery was lower abdomen (p<.001). Lower abdominal surgery used the highest amount of PCA (p<.001), and extremities and spinal surgery, the lowest amount of PCA and frequently stop using it (p<.001). The most common side effects were nausea and vomiting after surgery, with an incidence of 16.0% within 24 hours and 9.8% within 48 hours. The overall error caused by PCA was 1.5%, with 84.3% being caused by human errors. @*Conclusion@#With the pain management effect of APS nurses, patients used PCA more effectively. There were also fewer side effects and error rates compared to prior studies.Therefore, it is suggested that this system is safe and effective for pain management.

15.
Journal of Korean Academy of Nursing ; : 116-131, 2020.
Artigo em Coreano | WPRIM | ID: wpr-899481

RESUMO

PURPOSE@#This study aimed to develop a smartphone overdependence prevention program for college students based on the self-determination theory (SDT) and evaluate its effectiveness.@*METHODS@#A non-equivalent control group repeated measures design was used for the study. Participants were 64 university freshmen (experimental group: 29, control group: 35). The developed program consists of eight sessions conducted twice a week. The program was designed to promote autonomy, competence, and relatedness the three elements of the basic psychological needs of self-determination theory. The participants were assessed before the program, immediately after, and 1 and 3 months after the program. Data were collected from April 23 to September 14, 2018 and analyzed by performing a Chi-square test, Fisher's exact test, independent t-test, and repeated measures ANOVA using SPSS/WIN 23.0.@*RESULTS@#This study showed improvement in the basic psychological needs (F=3.90, p =.010) in the experimental group compared to the control group. Specifically, competence (F=2.93, p =.035), relatedness (F=2.89, p =.045), and self-regulatory ability (F=3.11, p =.028) improved significantly.@*CONCLUSION@#Study findings indicate thatthe smartphone overdependence prevention program based on the Self-determination theory could be an effective intervention for improving basic psychological needs and self-regulation ability. Therefore, this program could be an efficient strategy for smartphone overdependence prevention in university students.

16.
Journal of Korean Academy of Community Health Nursing ; : 460-470, 2019.
Artigo em Coreano | WPRIM | ID: wpr-785986

RESUMO

PURPOSE: This study was to identify the factors influencing the practice of respiratory infection prevention (RIP) for the elderly residing in rural areas.METHODS: The data were collected from 188 residents aged 65 years or older residing in the jurisdictions of four public health clinics in rural areas of C city, using a structured questionnaire for the period from December 1, 2018 to February 28, 2019. The collected data were analyzed with independent t-test, one-way ANOVA, Pearson's correlation coefficients, and hierarchical multiple regression analysis using SPSS/WIN 25.0 program.RESULTS: The score on knowledge of RIP was 8.82±1.36, while it was 4.53±0.47 for attitude, 3.78±0.66 for practice, and 3.78±0.69 for social capital. It was observed that the factors influencing the practice of RIP were attitude of RIP (β=.38, p < .001), social capital (β=.29, p < .001), family type (β=−.19, p=.002), and subjective health status (β=.15, p=.035), while the explanatory power of the model was 47%.CONCLUSION: Consequently, to enhance the practice of RIP for the elderly residing in rural areas, it is necessary to develop programs considering social and environmental characteristics of rural areas based on their attitude of RIP, social capital, family type and subjective health status.

17.
Journal of Korean Academy of Psychiatric and Mental Health Nursing ; : 26-36, 2019.
Artigo em Coreano | WPRIM | ID: wpr-740854

RESUMO

PURPOSE: Smartphone overdependence in young adults is a growing issue, that requires a vigorous approach to manage its associated problems in the affected ones. This study was designed to suggest a detailed direction to help university students with smartphone overdependence, who would be internally motivated through satisfying their basic needs based on the self-determination theory (SDT). METHODS: The data were collected via face-to-face interviews with twenty program providers, who have managed the program for preventing and treating the smartphone overdependence. All interviews were audio-recorded and transcribed. The data were analyzed using directed qualitative content analysis. RESULTS: One core category emerged from the findings: ‘Empowering motivation of autonomous actor of change associated with environmental context,’ which three generic categories and seven subcategories supported. Apart from the three basic needs in the SDT, autonomy, relatedness, and competence, no additional concepts were mentioned, but the participants complained about the practical difficulties of running programs with non-motivated students. CONCLUSION: Our study findings emphasize that research and clinical practice for young people with smartphone overdependence should focus more on developing detailed program contents synchronized with theoretical and conceptual guidance.


Assuntos
Humanos , Adulto Jovem , Comportamento Aditivo , Competência Mental , Motivação , Pesquisa Qualitativa , Corrida , Smartphone
18.
Korean Journal of Occupational Health Nursing ; : 197-207, 2019.
Artigo em Coreano | WPRIM | ID: wpr-786327

RESUMO

PURPOSE: This study aimed to examine the relationship between organizational health (OH), safety climate (SC), the nursing working environment (NWE), and engagement in patient safety management activities (PSMA) among operating room nurses and identify the factors that predict engagement in PSMA.METHODS: From August 10th to 25th, 2018, 176 operating room nurses who were working in tertiary and general hospitals responded to a structured questionnaire. Using SPSS/WIN 25.0, the collected data were subjected to independent-samples t-test, one-way analysis of variance, Scheffé test, and Pearson's correlational and multiple stepwise regression analyses.RESULTS: OH and SC were significantly correlated with engagement in PSMA. The factors that predicted engagement in PSMA were OH, NWE, participation in accreditation, years of work experience, and hospital size; together, they explained 17% of the variance in engagement in PSMA.CONCLUSION: This study revealed that OH has a significant influence on engagement in PSMA among operating room nurses. Therefore, hospitals should aim to create healthy working environments to promote engagement in PSMA among operating room nurses, actively delegate responsibilities to increase their level of participation in accreditation, and implement strategies that maintain high levels of nurse retention.


Assuntos
Humanos , Acreditação , Clima , Tamanho das Instituições de Saúde , Hospitais Gerais , Enfermagem , Salas Cirúrgicas , Segurança do Paciente , Gestão da Segurança
19.
Korean Journal of Occupational Health Nursing ; : 197-207, 2019.
Artigo em Coreano | WPRIM | ID: wpr-918089

RESUMO

PURPOSE@#This study aimed to examine the relationship between organizational health (OH), safety climate (SC), the nursing working environment (NWE), and engagement in patient safety management activities (PSMA) among operating room nurses and identify the factors that predict engagement in PSMA.@*METHODS@#From August 10th to 25th, 2018, 176 operating room nurses who were working in tertiary and general hospitals responded to a structured questionnaire. Using SPSS/WIN 25.0, the collected data were subjected to independent-samples t-test, one-way analysis of variance, Scheffé test, and Pearson's correlational and multiple stepwise regression analyses.@*RESULTS@#OH and SC were significantly correlated with engagement in PSMA. The factors that predicted engagement in PSMA were OH, NWE, participation in accreditation, years of work experience, and hospital size; together, they explained 17% of the variance in engagement in PSMA.@*CONCLUSION@#This study revealed that OH has a significant influence on engagement in PSMA among operating room nurses. Therefore, hospitals should aim to create healthy working environments to promote engagement in PSMA among operating room nurses, actively delegate responsibilities to increase their level of participation in accreditation, and implement strategies that maintain high levels of nurse retention.

20.
Soonchunhyang Medical Science ; : 15-21, 2018.
Artigo em Inglês | WPRIM | ID: wpr-715119

RESUMO

OBJECTIVE: Contrast-induced nephropathy (CIN) frequently occurs after percutaneous intervention. Objective of this study was to investigate the usefulness of serum cystatin C, neutrophil gelatinase-associated lipocalcin (NGAL), urinary kidney injury molecule-1 (KIM-1), and interleukin-18 (IL-18) as early predictors for CIN after percutaneous coronary intervention (PCI). METHODS: In 53 patients who underwent PCI were enrolled. Serum creatinine and cystatin C level were measured immediately before, and 24 hours and 48 hours after catheterization. Serum NGAL, urinary KIM-1, and IL-18 were measured immediately before, and 4 hours, 24 hours, and 48 hours after catheterization. CIN was defined as a rise in creatinine 0.5 mg/dL or 25% above baseline. RESULTS: CIN occurred in four patients (7.5%). Serum cystatin C levels were higher at 24 hours and 48 hours in CIN patients than in those without CIN (P<0.05). Serum NGAL levels were higher at 48 hours in CIN patients than in those without CIN. Urinary KIM-1 levels were higher at 48 hours in CIN patients than in those without CIN. There were no significant markers of CIN on multi-variate analysis. CONCLUSION: In this study, the occurrence of CIN after PCI was 7.5%. Although there were some time-course changes in serum cystatin C and urinary KIM-1 after PCI, there was no significant predictor for CIN after PCI.


Assuntos
Humanos , Cateterismo , Catéteres , Meios de Contraste , Creatinina , Cistatina C , Interleucina-18 , Rim , Neutrófilos , Intervenção Coronária Percutânea
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