Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Adicionar filtros








Intervalo de ano
1.
Journal of Legal Medicine and Forensic Sciences [The]. 1998; 10 (1-4): 341-351
em Inglês | IMEMR | ID: emr-48244

RESUMO

Sixty mature albino rats were divided equally into five test groups and one control group. Acetaminophen was given orally [100 mg/kg] to rats of the five test groups. N-acetylcysteine [150mg/kg], zinc sulphate [15mg/kg]; combined zinc sulphate and N-acetylcysteine with the same doses and hepanox [150 mg/kg] ere given orally one hour after the toxic acetaminophen dose to rats of the second; third; fourth and fifth groups respectively. Statistical analysis of values of serum Alt, ast, ldh AND g-6-P-D showed high signifidcant elevation in the first test group [acetaminoiphen], significant decrease in the second DD[N-acetylcysteine] and third [zinc sulphate] groups and dramatic significant improvement in the fourth [combined N-acetylcysteine and zinc sulphate] and fifth [hepanox] groups. All biochemical results coincided completely and confirmed by the histopathological findings in the livers of the studied rats


Assuntos
Animais de Laboratório , Fígado/toxicidade , Substâncias Protetoras , Acetilcisteína , Sulfato de Zinco , Silimarina , Estudo Comparativo , Testes de Função Hepática , Histologia , Antioxidantes , Ratos
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA