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Arq. neuropsiquiatr ; 59(3B): 691-695, Sept. 2001. ilus, tab
Artigo em Inglês | LILACS | ID: lil-295832

RESUMO

The aim of the study was to detect neurological abnormalities in human immunodeficiency virus (HIV) infected children. This was achieved by a prospective evaluation, from November/1995 to April/2000, of 43 HIV infected children (group I) and 40 HIV seroreverters children (group II) through neurological exam and neurodevelopmental tests: Denver Developmental Screening Test (DDST) and Clinical Adaptive Test / Clinical Linguistic and Auditory Milestone Scale (CAT/CLAMS). A control group (III), of 67 children, were evaluated by CAT/CLAMS. Hyperactivity, irritability and hypotonia were the findings on neurological examination, without statistical differences between group I and II. On CAT/CLAMS, the group I developmental quotient (DQ) was significantly lower than the other groups. The same occurred in DDST, with group I presenting significantly more failures than group II. Nineteen HIV children of group I had brain computed tomographic scan, with abnormalities in three of them (basal ganglia calcification, white matter hypodensity and asymmetry of lateral ventricles). We conclude that in HIV infected children a neurodevelopment delay occur early in the disease, and it can be detected by screening tests


Assuntos
Recém-Nascido , Lactente , Pré-Escolar , Criança , Humanos , Masculino , Feminino , Deficiências do Desenvolvimento/diagnóstico , Infecções por HIV/complicações , Transmissão Vertical de Doenças Infecciosas , Estudos de Casos e Controles , Desenvolvimento Infantil , Estudos Transversais , Deficiências do Desenvolvimento/etiologia , Seguimentos , Testes Auditivos , Infecções por HIV/transmissão , Soronegatividade para HIV , Desenvolvimento da Linguagem , Testes Neuropsicológicos , Estudos Prospectivos , Tomografia Computadorizada por Raios X
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