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1.
Rev. méd. Chile ; 126(11): 1291-9, nov. 1998. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-243720

RESUMO

Background: Chilean aboriginal populations (Mapuche) predominantly live in the region of Araucanía, in the southern part of the country. Their cardiovascular risk factors have not been systematically assessed. Aim: To study the prevalence of cardiovascular risk factors in the Mapuche population. Subjects and methods: Blood pressure, weight, height, dietary habits, fasting serum total cholesterol, HDL cholesterol and triglycerides were measured in 1.948 adults living in 28 Mapuche communities. Results: Thirteen percent of males and 16 percent of females had high blood pressure. Body mass index was 25.5 kg/m2 in males and 28.1 kg/m2 in females. Forty five percent of women and 24 percent of men were classified as obese. Mean serum total cholesterol was 186.7ñ9.6 mg/dl, HDL cholesterol was 58.7ñ30.7 mg/dl, total cholesterol/HDL cholesterol was 3.4ñ2 and triglycerides were 155.2ñ91.2 mg/dl. Twenty eight percent of males and 9.6 percent of females smoked. Conclusions: Mapuche individuals have higher levels of HDL cholesterol, a better total cholesterol/HDL cholesterol ratio and lower frequency of smoking than non aboriginal Chileans subjects


Assuntos
Humanos , Masculino , Feminino , Adulto , Doenças Cardiovasculares/epidemiologia , Indígenas Sul-Americanos/estatística & dados numéricos , Fumar/epidemiologia , Colesterol/sangue , Estado Nutricional , Fatores de Risco , Obesidade/sangue , Distribuição por Idade , Distribuição por Sexo , Hipertensão/epidemiologia , Lipídeos/sangue , Pressão Sanguínea
2.
Rev. méd. Chile ; 122(10): 1147-52, oct. 1994. tab
Artigo em Espanhol | LILACS | ID: lil-143990

RESUMO

Due to differences in treatment effect in studies on the effectiveness of digoxin in patients with congestive heart failure in sinus rhythm, a cross-over placebo-controlled randomized double blind clinical trial was performed. Thirty one patients, without previous treatment with digoxin, in New York Heart Association (NYHA) functional class II to IV, with a dilated left ventricle and/or ventricular systolic dysfunction were included. Patients received digoxin, adjusted for blood levels, or placebo, during an 8 week period, prior to crossing over to the other treatment for another 8 weeks. The order of tretments was randomly allocated. Outcome measurement were performed at the end of each 8 week period. Digoxin, compared with placebo, improved NYHA class, 6,9 por ciento vs 41.4 por ciento (p=0.013) and increased the treadmill exercise time, 406 ñ 204 s vs 484 ñ 185 s (p=0.003). During the digoxin treatment the left ventricular and systolic diameter was reduced from 52.9 ñ 8.9 to 50.1 ñ 9.7 mm (p=0.009). No significant difference was observed in the left ventricular end diastolic diameter (LVED) of the left ventricle and in a estimation of quality of life. In conclusion, digoxin treatment produced a significant improvement in functional capacity, exercise time and left ventricular performance


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Digoxina/farmacologia , Insuficiência Cardíaca/tratamento farmacológico , Placebos/administração & dosagem , Qualidade de Vida , Ecocardiografia , Cardiomiopatia Dilatada/tratamento farmacológico , Capacidade Vital/efeitos dos fármacos , Ergometria , Doença das Coronárias/tratamento farmacológico , Digoxina/administração & dosagem , Digoxina/sangue , Hemodinâmica , Insuficiência da Valva Aórtica/tratamento farmacológico , Insuficiência da Valva Mitral/tratamento farmacológico , Ruídos Cardíacos
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