Pemphigus Vulgaris in a Neonate and his Mother.

Background: Neonatal pemphigus is a rare, transient blistering condition due to transplacental transfer of maternal autoantibodies. Case characteristics: A male neonate born to a mother with oral pemphigus was noticed to have multiple lesions. Observation: Multiple flaccid bullae were noticed on the face, scalp, trunk and extremities with clear fluid and few areas of erosions. Outcome: All lesions resolved at the end of one week with conservative management. Message: Maternal pamphigus may rarely involve her newborn infant; it resolves on its own.

Age related seroprevalence of antibodies to varicella in India.

OBJECTIVE: To determine the age related prevalence of Varicella Zoster Virus (VZV) antibodies in India. SETTING: This was a cross sectional multicentric study performed in 4 major cities of India: Calcutta (outpatients), Mumbai (outpatients), Lucknow (walk-in patients to a diagnostic laboratory, orphanage and factory workers) and Bangalore (outpatients and walk-in patients to a diagnostic laboratory). METHODS: A total of 1609 volunteers from birth to 40 years of age were included into the study. IgG antibodies against VZV were determined using commercial kits (ELISA-Enzygnost). RESULTS: Overall seroprevalence of anti VZV antibodies was 68. 22percnt. The age related seroprevalence rate of anti VZV antibodies was 29percnt in the age group of 1-5 years, 51.1percnt in 5-10 years, 71.7percnt in 11-15 years, 79.8percnt in 16-20 years, 88.1percnt in 21-30 years and 91.1percnt in 31-40 years. CONCLUSION: A significant proportion of adolescents and adults are susceptible to varicella in India, as in other tropical countries