RESUMO
Objective: to detect the impact of acne vulgaris on quality of life and assess correlation between disease severity, complications and decreased life quality
Methods: this cross-sectional study of one-year duration involving acne patients of 18-30 years was carried out after institutional Ethics Committee clearance. After written informed consent, patients filled a proforma including demographic data, treatment and previous psychiatric history. Clinical grade of acne and severity of pigmentation and scarring were noted. Acne severity was classified as mild, moderate or severe and DLQI was noted. Statistical analysis was performed with the Statistical Package for the Social Sciences [SPSS version 15.0], Chi-square test and Pearson's correlation coefficient
Results: overall mean DLQI was 7.84 [females 8.02, males 7.82] showing no significant difference between the genders. There was no association seen between DLQI scores severity and complications like pigmentation [p=0.198] and scarring [p=0.095]. There was significant association between severity of acne grades and DLQI scores [p=0.014]
Limitation: the study population was restricted to patients visiting our outpatient department. Only DLQI questionnaire was used for evaluation, which could detect psychosocial problems, but not depression or anxiety without clinical assessment
Conclusion: our study confirms a negative impact of acne on quality of life substantiating a holistic approach treating physique and psyche for well-being of the person
RESUMO
To compare the efficacy and safety of 2% ketoconazole soap in treatment of tinea versicolor [TV] and to compare it with stat 400mg dose of ketoconazole. Patients of TV confirmed by potassium hydroxide [KOH] mount were divided by block randomization into 2 groups. Group 1 received 400mg of oral ketoconazole single dose and a non-medicated soap for daily bath. Group 2 received 2% ketoconazole soap for daily bath. The lather from the soap while bathing was to be left on the skin for 3 minutes. Patients were assessed at the end one month and KOH repeated from index lesion. Twelve patients out of 25 completed the study, 6 in each group. Four patients [66%] were mycologically cured in group 1 while two patients [34%] were mycologically cured in group 2. All these patients were compliant with the usage of soap. Ketoconazole soap is at best an adjunct in the treatment of TV. It might however be useful in the prophylactic management of patients with chronic TV as bathing is almost a daily routine in most patients especially in tropics. Further studies are required in this aspect