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Journal of Korean Medical Science ; : 1187-1193, 2013.
Artigo em Inglês | WPRIM | ID: wpr-173137

RESUMO

The prevalence of antibiotic resistance is higher in patients undergoing renal replacement therapy (RRT) than in patients who did not undergo RRT. We investigated the presence of KP (Klebsiella pneumoniae) in patients who underwent RRT. All data were collected retrospectively by accessing patient medical records from 2004 to 2011 for the culture results of all patients who were positive for KP. We grouped the patients by the presence of extended-spectrum beta-lactamase (ESBL) into a KP ESBL(-) group (KP[-]) and a KP ESBL(+) group (KP[+]). In total, 292 patients (23.1%) were in the KP(+) group, and 974 patients (76.9%) were in the KP(-) group. A greater percentage of KP(+) was found in patients who underwent RRT (7.5%) than in patients who did not undergo RRT (3.2%) (OR, 2.479; 95% CI,1.412-4.352). A Cox's hazard proportional model analysis was performed, and for patients with pneumonia, the risk of KP(+) was 0.663 times higher in patients who had lower albumin levels, 2.796 times higher in patients who had an inserted Levin tube, and 4.551 times higher in patients who underwent RRT. In conclusion, RRT can be a risk factor for KP(+) in patients with pneumonia.


Assuntos
Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estimativa de Kaplan-Meier , Falência Renal Crônica/microbiologia , Infecções por Klebsiella/epidemiologia , Klebsiella pneumoniae/enzimologia , Razão de Chances , Pneumonia/diagnóstico , Prevalência , Modelos de Riscos Proporcionais , Terapia de Substituição Renal , Estudos Retrospectivos , Fatores de Risco , Albumina Sérica/análise , beta-Lactamases/metabolismo
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