Soft tissue giant cell tumour revisited - a case report

Giant cell tumour of soft tissue [GCT-ST] is an uncommon entity which histopathologically resembles bony GCT. We report a case of giant cell tumour in a 45-year-old male patient who presented to the dermatology department with a gradually enlarging painless, smooth swelling over second toe of left foot. Histopathology revealed it to be giant cell tumour of soft tissue.

Psoriasis and subclinical atherosclerosis: a significant association

To identify the presence of subclinical atherosclerosis by measuring carotid intima medial thickness [IMT] in patients with psoriasis attending the dermatology clinic of a tertiary care hospital. 30 patients who fulfilled the exclusion and inclusion criteria were recruited. 5 healthy persons devoid of known cardiovascular risk factors were registered as controls. Intima medial thickness of common carotid and vertebral arteries of both sides were measured by B mode ultrasound. Result showed that IMT and velocity of left common carotid artery and velocity in right vertebral artery were significantly greater in psoriatic patients than control group and psoriatic patients had 0.8 times greater risk of developing atherosclerosis than control group. Subclinical atherosclerosis remains undiagnosed in patients of psoriasis who usually lack the established risk factors for cardiovascular disease

Acquired giant tufted angioma: a rare entity

Tufted angioma is an uncommon benign vascular tumour encountered usually in infancy and early childhood. Lesions are mostly confined to the trunk and face and generally not larger than 10 cm in diameter. Our case was about an 11-year-old boy who presented with a very large, enhancing, reddish brown coloured, tender plaque on loin. Histopathology revealed circumscribed, multiple foci of closely set vascular channels giving the canon ball appearance suggestive of tufted angioma. Giant tufted angiomas are rare and hence reported

Adult-onset Gunther's disease [congenital erythropoietic porphyria] in a 37-year-old man: a case report

A 37-year-old man presented with multiple blisters and ulcerations over the sun exposed skin of 2 years duration. His clinical, radiological, hematological features, fluorescent microscopy of urine and histopathology of subepidermal blister with PAS-positive material deposited in the upper dermis in a perivascular and periadnexal distribution were suggestive of congenital erythropoietic porphyria, was treated with beta carotene and advised to avoid sun exposure by using sun protective clothing. We repot this case because of its rarity