Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 3 de 3
Filtrar
Adicionar filtros








Intervalo de ano
1.
Obstetrics & Gynecology Science ; : 266-273, 2014.
Artigo em Inglês | WPRIM | ID: wpr-174660

RESUMO

OBJECTIVE: The aim of this study was to determine the distribution of T-lymphocytes and their relationship with clinicopathologic factors in endometrial carcinoma. METHODS: Samples were collected from 89 patients with endometrial endometrioid adenocarcinoma treated in Pusan National University Hospital from 2004 to 2011. Normal endometrial tissues were obtained from 30 hysterectomized women with benign adnexal masses and served as controls. Paraffin-embedded sections were immunohistochemically stained for CD8 (cytotoxic) and CD4 (helper) T-lymphocytes. The relationship of these cells with stage, histological grade, myometrial invasion, and lymph node metastasis was analyzed. RESULTS: The proportion of CD8+ and CD4+ lymphocytes in the endometrial endometrioid adenocarcinoma tissues was 67.4% (60/89) and 44.9% (40/89), respectively, which was significantly higher (P<0.05) than in the control group. The extent of CD8+ lymphocyte expression was negatively correlated with histologic grade, myometrial invasion, and lymph node metastasis. The proportion of infiltration of the CD4+ lymphocytes was negatively correlated with histologic grade and myometrial invasion. CONCLUSION: The high rate of infiltration of T-lymphocytes was negatively correlated with histologic grade, myometrial invasion, and lymph node metastasis. Our findings suggest that tumor-infiltrating T-lymphocytes may be used as pathologic prognostic factors in endometrial carcinoma.


Assuntos
Feminino , Humanos , Adenocarcinoma , Carcinoma Endometrioide , Neoplasias do Endométrio , Linfonodos , Linfócitos , Metástase Neoplásica , Linfócitos T
2.
Korean Journal of Medicine ; : 833-840, 1997.
Artigo em Coreano | WPRIM | ID: wpr-166459

RESUMO

OBJECTIVES: The aim of this study was to evaluate the prevalence and risk factors of hepatitis C virus(HCV) infection in patients on chronic hemodialysis. METHODS: We measured antibody to HCV using second generation enzyme immunoassay(ELISA) test or radioimmunoassay(RIA) and hepatitis B surface antigen, serum values of AST, ALT in 224 patients of six urban hemodialysis units. We also investigated some clinicai parameters such as age, sex, duration and frequency of hemodialysis, the amount of blood transfusion, and hemodialysis of infected patients on separate machines. RESULTS: 1) 33 of 224 patients(14.7%) were positive for HCV antibody. 2) The prevalence of HCV antibody were most significantly correlated with duration of hemodialysis and less significantly with frequency of hemodialysis, amount of blood transfusion but not correlated with age, sex and level of liver enzyme. 3) The prevalence of HCV antibody was significantly higher in a center which did not separate dialysis machine for HCV antibody positive patients than centers which did. CONCLUSION: Th prevalence of HCV antibody was most signficantly correlated with duration of hemodialysis. We suggest that environmental factor of hemodialysis unit may play major role in HCV infection of hemodialysis patients. So the importance of separate dialysis machine from HCV antibody positive patients should be emphasized.


Assuntos
Humanos , Transfusão de Sangue , Diálise , Hepacivirus , Antígenos de Superfície da Hepatite B , Hepatite C , Hepatite , Fígado , Prevalência , Diálise Renal , Fatores de Risco
3.
Korean Journal of Nephrology ; : 104-109, 1993.
Artigo em Coreano | WPRIM | ID: wpr-165402

RESUMO

No abstract available.


Assuntos
Injúria Renal Aguda , Rabdomiólise , Tétano
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA