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Purpose@#Sleep disturbance is among commonly reported symptoms associated with leukemia and its treatment. The purpose of this study was to identify the symptom experience, anxiety and depression, and sleep disturbance in patients with acute leukemia undergoing chemotherapy. @*Methods@#A total of 82 patients with acute leukemia who were undergoing chemotherapy were recruited. Data were collected using a self-reported questionnaire, which included the M. D. Anderson Symptom Inventory, the Hospital Anxiety Depression Scale, the Pittsburgh Sleep Quality Index, and the Patient Activation Measure 13. @*Results@#Sleep disturbance and symptom experience, and anxiety and depression were shown to be positively correlated, and patient activation was shown to be negatively correlated. Use of sleeping pills and symptom severity were significantly associated with sleep disturbance. @*Conclusion@#The psychological and physical symptoms patients experience during treatment should be accurately identified, and effective nursing interventions should be provided. In addition, patient activation in patients with acute leukemia under inpatient treatment was not correlated with symptoms. However, supportive care should be provided to develop and accurately measure patient activation tools suitable for disease characteristics to increase patient activation.
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Purpose@#Sleep disturbance is among commonly reported symptoms associated with leukemia and its treatment. The purpose of this study was to identify the symptom experience, anxiety and depression, and sleep disturbance in patients with acute leukemia undergoing chemotherapy. @*Methods@#A total of 82 patients with acute leukemia who were undergoing chemotherapy were recruited. Data were collected using a self-reported questionnaire, which included the M. D. Anderson Symptom Inventory, the Hospital Anxiety Depression Scale, the Pittsburgh Sleep Quality Index, and the Patient Activation Measure 13. @*Results@#Sleep disturbance and symptom experience, and anxiety and depression were shown to be positively correlated, and patient activation was shown to be negatively correlated. Use of sleeping pills and symptom severity were significantly associated with sleep disturbance. @*Conclusion@#The psychological and physical symptoms patients experience during treatment should be accurately identified, and effective nursing interventions should be provided. In addition, patient activation in patients with acute leukemia under inpatient treatment was not correlated with symptoms. However, supportive care should be provided to develop and accurately measure patient activation tools suitable for disease characteristics to increase patient activation.
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Background@#To identify the differences in the vancomycin pharmacokinetics between multiple trauma patients and medically ill patients in the intensive care unit (ICU) stratified by the use of continuous renal replacement therapy (CRRT), and the factors affecting vancomycin clearance (CLvan ). @*Materials and Methods@#All the included patients received at least three consecutive doses of vancomycin, then, therapeutic drug monitoring was conducted. Patients' serum vancomycin trough levels and other clinical variables were identified retrospectively. The vancomycin pharmacokinetics and associated factors were compared and analyzed between trauma ICU (TICU) and medical ICU (MICU) patients. @*Results@#In the non-dialyzed group, the CLvan was higher among the TICU patients than the MICU patients. However, in the continuous renal replacement therapy group, there was no significant difference in the CLvan between the multiple trauma and medically ill patients. The only factor associated with CLvan in the non-dialyzed group was creatinine clearance; none of the factors was associated with CLvan in the CRRT group. @*Conclusion@#In the case of non-dialyzed patients in the TICU, vancomycin dosages must be adjusted, depending on the patient's actual body weight changes. In the case of patients undergoing CRRT in both ICUs, vancomycin can be infused with fixed doses regardless of the patients' characteristics.
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PURPOSE: The purpose of this study was to identify menstrual distress, coping method and relief of symptoms among female nurses who worked with 3-shift. METHODS: A total of 185 participants were recruited from November 18, 2011 to January 30, 2012. The measurement included menstrual distress and coping method questionnaire and relief of symptoms. The data were analyzed using t-test, ANOVA, Pearson's correlation coefficients with SPSS 19.0. RESULTS: The level of menstrual distress was moderate (mean 3.0), and there were significant differences in menstrual distress by age, education, stress, regularity of menstrual cycle. Among the coping methods, coping according to menstrual cycle specific was the most frequently used, followed by active recognizing coping, active behavioral coping, and avoidance coping. Among the degree of symptom relief, symptom relief score was the highest when used coping according to menstrual cycle specific. Menstrual distress was associated with stress, adequate amount of sleep, dysmenorrhea and number of coping method total. CONCLUSION: Nurses experienced moderate levels of menstrual distress and used various types of coping to relieve it. There is a need for hospital nurses to develop an effective nursing intervention to relieve the menstrual distress and utilize active coping methods.