Genotype, Coagulase Type and Antimicrobial Susceptibility of Methicillin-Resistant Staphylococcus aureus Isolated from Dermatology Patients and Healthy Individuals in Korea

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent dermatology pathogens in hospitals and increasingly recognized in communities. We determined PFGE pattern of SmaI-restricted genomic DNA, coagulase type, and antimicrobial susceptibility of MRSA isolated in 2008 from dermatology inpatients and healthy hospital employees in A Hospital and from primary school children in Iksan city, Korea. Overall, the isolation rate of MRSA was 3.8% from the 788 normal persons: 4.9% from hospital employees and 1.1% from primary school children. MRSA was isolated in six of 13 (46.2%) family members of four school children with MRSA. The most prevalent coagulase serotype was II from patients and V from healthy individuals. Ten of twenty and six of twenty MRSA isolates from patients and from healthy personnel, respectively, had identical PFGE patterns, suggesting that these are originated from identical clones. Against MRSA from patients, only vancomycin was the most active (MIC range or =90% to amikacin, clindamycin, ciprofloxacin, erythromycin, fusidic acid, gentamicin and tetracycline. In conclusion, the MRSA carriage rates of healthy hospital workers were relatively high, 2.3~7.7%, depending on groups. Family members of a few primary school children with MRSA showed a high carriage rate, suggesting that intrafamily transmission occurred. MRSAs isolated from dermatology inpatients were relatively more resistant to various antimicrobial agents, including mupirocin, but all isolates were susceptibility to vancomycin.

A Case of Loeffler's Endocarditis with Acute Obstruction of Common Iliac Artery

Loeffler's endocarditis is a recognized complication of diseases associated with eosinophilia. This disease is considered to be a part of the idiopathic hypereosinophilic syndrome, which is characterized by persistently elevated blood eosinohil counts with symptoms and signs of organ involvement especially in the heart, nervous system, and bone marrow. We have experienced a case of Loeffler's endocarditis in a 51 years old man who complained of leg pain due to acute closure of left iliac artery by emboli. We found left ventricular mural thrombus by echocardiography and confirmed Loeffler's endocarditis by endomyocardial biopsy. We present a case with the review of literatures.

A Case of Renal Cell Carcinoma in Autosomal Dominant Polycystic Kidney Disease Hemodialyzed / 대한신장학회잡지

The development of renal cell carcinoma in auto-sornal dominant polycystic kidney disease hemodialyzed was rarely found. A sixty-six year old man has been hemodialyzed for four years. His end-stage renal failure was caused by autosomal dominant polycystic kidney disease. He presented the sudden onset of gross hematuria which does not cause any pain. Radi-ological examination showed the possibility of renal cell carcinoma in autosomal dominant polycystic kidney disease. The renal cell carcinoma was confirmed through nephrectomy and pathological examination. In this article, we present a case of renal cell carcinoma in autosomal dominant polycystic kidney disease hemodialyzed.

Safety of Radiofrequency Catheter Ablation in Patients with Supraventricular Tachycardia Confirmed by Means of Echocardiography

BACKGROUND: Radiofrequecy(RF) catheter ablation is the choice of treatment of refractory supraventricular tachycardia. Althogh catheter ablation is invasive, it is well-known that this procedure is safe. However RF catheter ablation may provoke some adverse conditions. The purpose of this study was to assess functional and morphologic changes shortly after radiofrequency catheter ablation in patients with supraventricular tachycardia by means of two-dimensional echocardiography. METHOD: Echocardiogram underwent 1 day before and within 3 days after RF catheter ablation. Cardiac chamber size, wall thickness, and valve motion in the M-mode were Measured. Left ventricular volume, area, dimension, pericardial effusion and segmental wall motion were measured by means of two-dimensional echocardiography and valve incompetence were also measured with color Doppler echocardiography. RESULTS: New echocardiographic abnormalities were observed in 4(5.4%) among 73 patients. One mild aortic regurgitation,one increase in severity of tricuspid imcompetence, one increase in severity of mitral regurgitation and one mild pericardial effusion were found. CONCLUSION: We concluded that echocardiographic changes after radiofrequency ablation are rate and of minor significance.

The Clinical Application and Usefulness of transesophageal Echocardiography

BACKGROUND: During the past few years, transesophageal echocardiography(TEE) became one of most impartant method to detect various cardiac disease. But it was performed less than 10% of transthoracic echocardiography(TTE) in most of echocardiographic laboratoties because of major and minor complicatios associated with this procedure. The purposes of this study are to evaluate the clinical applications and the usefulness of transesophageal echocardiography in various cardiac disorders. METHOD: From 1990 to 1995, 942 cases were included in this study. All subjects were taken TTE and TEE simultaneously The causes of request, related side effect, cause of failed cases, and the benefit of TEE compared to TTE were analysed. The benefit of TEE were classified into major and minor benefit. Major benefit was defined as to diagnose the disease or to change the therapeautic method by TEE. Minor benefit was defined as to have additional findings by TEE whic could not be enrolled in major benefit. RESULTS: 1) The success rate of TEE was 95.5%(900/942). In 42 failed cases(4.5%), 19 were interrupted procedure earlier, 16 were failed to insert the TEE probe, 4 cases showed arrhythmia, and 3 cases had esophageal stricture or varices. 2) The causes of request were to assess the prosthetic valve function(35.5%), cardiac source of embolism(23.7%), valvular heart disease(22.7%), congenital heart disease(10.2), aortic disease(2.7%), endocarditis(2.3%), cardiac mass(1%), and coronary artery disease(1%), in orders. 3) The benefit of TEE was 77%, congenital heart disease was revealed greatest benefit(97%), but major benefit was highest for the evaluation of cardiac source of emboli(100%). CONCLUSION: TEE was very useful method for the detection of intra-cardiac and aortic abnormalities. TEE is a relatively safe procedure but it is a semi-invasive method and has few complications. So it is wise to apply TEE as adjuvant method of TTE.

The Characteristics of Primary Cardiac Tumors Occured in Korean People

OBJECTIVES: Primary cardiac tumors are rare, being found in approimately 1 in 10,000 to 33 in 1,000 routine autopsies in patients of all ages. The purpose of this study is to evaluate the status of primary cardiac tumor in Korea, Their clinical and pathological characteristics. We analysed our 13 cases of primary cardiac tumors confirmed by operative findings, and all cases which were published in several literatures. METHOD: Thirteen cases of primary cardiac tumors confirmed by pathologic findings from 1982 in keimyung university hospital, and 116 cases of published data from 1962 were reviewed their pathologic and clinical findings. RESULTS: One hundred and twenty nine cases were included in this study, The age was ranged from 15 dyas to 75 years old. 45 cases(35%) were male and 84(65%) were female. 119 cases(92.2%) were revealed benign tumor : 115 myxoma, 2 rhabdomyoma, 1 lipoma and 1 fibroma. 10 cases(7.8%) were malignant tumors : 4 angiosarcoma, 2 fibrous histiocytoma, 2 rhabdomyosarcoma, 2 fibrosarcoma. The most common site of benign tumor was left atrium, and of malignant tumor was right atrium. CONCLUSION: Most of primary cardiac tumors were benign. And left atrial myxoma was most common primary cardiac tumor. Angiosarcoma was most common malignant tumor, occured in right atrium most frequently.

The Pathogenesis of COPD / 결핵

No abstract available.