RESUMO
We report a case of an intravascular hemolytic reaction attributable to anti-Jk(b) antibodies that were not detected using an enzyme phase antibody identification test. A 61-year-old male who had received two units of red blood cells was admitted to the emergency room because his urine was dark. LISS/Coombs gel column agglutination tests suggested the presence of anti-Jk(b) and anti-E antibodies. However, his serum was negative for the Jk(b) antigen when an enzyme phase test was performed. A positive reaction was evident, however, when EDTA-treated plasma was tested; this excluded any possible complement-mediated reaction. The patient was diagnosed with an intravascular hemolytic transfusion reaction, caused by anti-Jk(b), and was later discharged without specific complications after receiving antigen-negative blood transfusions.
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Testes de Aglutinação , Anticorpos , Incompatibilidade de Grupos Sanguíneos , Transfusão de Sangue , Ácido Edético , Serviço Hospitalar de Emergência , Eritrócitos , Sistema do Grupo Sanguíneo Kidd , PlasmaRESUMO
Lutheran a antigen (Lua) is detected in 6 to 8% of Caucasians and Africans. In Korean and other Asian populations, it is very rare or nearly absent. Therefore, although Lua has a considerable immunizing capacity, sensitization to Lua is a rare event. Here we report on a rare case of anti-Lua in a 70 year-old female patient with Lu (a-/b+) phenotype and review the relevant literature. Due to the paucity of Lua positive panel cells in antibody screening and identification tests, detection of this rare antibody to Lua antigen is not feasible. Therefore, we should keep in mind the possibility of the misleading false negative result in detection of antibody to this low incidence antigen.
Assuntos
Feminino , Humanos , Povo Asiático , Incidência , Sistema do Grupo Sanguíneo Lutheran , Programas de Rastreamento , Fenótipo , ProtestantismoRESUMO
Bacillus species are ubiquitous in nature, and they are frequently considered as contaminants. Paenibacillus alvei is a spore forming bacterium that swarms vigorously on routine culture media. P. alvei has been reported as the cause of human infections in only a few cases. We report a case of cellulitis caused by P. alvei on right leg in an immunocompetent 62-year-old man.