RESUMO
We are reporting a rare case of primary mucocutaneous histoplasmosis. A 47-year-old male with a part-time job of rearing pigeons presented with a non-healing oral ulcer with no associated systemic symptoms. Differential diagnosis of oral ulcerative lichen planus, squamous cell carcinoma and mucocutaneous leishmaniasis was considered. Histopathology showed multiple organisms with a peripheral halo, stained strongly with Gomori methenamine silver stain.
Assuntos
Antifúngicos/uso terapêutico , Histoplasmose/complicações , Humanos , Masculino , Pessoa de Meia-Idade , Úlceras Orais/microbiologiaRESUMO
A 38-year-old female presented with hyperpigmented velvety plaques on the nape and the sides of the neck with diffuse pigmentation of the face and flexures suggestive of acanthosis nigricans. The dorsa of both the hands showed increased rugosity, hyperpigmentation and hyperkeratosis of the palms, suggestive of tripe palms. Investigations revealed multiple secondaries in the liver. Histopathology showed the secondaries to be from adenocarcinoma of the gastrointestinal tract.
Assuntos
Acantose Nigricans/diagnóstico , Adenocarcinoma/secundário , Adulto , Biópsia por Agulha , Feminino , Seguimentos , Humanos , Imuno-Histoquímica , Laparotomia/métodos , Neoplasias Hepáticas/patologia , Síndromes Paraneoplásicas/patologia , Medição de Risco , Neoplasias Gástricas/patologiaRESUMO
A 2(1/2)-year-old child presented with multiple discrete granulomatous lesions on the face and flexural regions since the age of 2 months along with lymphadenopathy. The patient also had recurrent bouts of pyodermas and respiratory tract infections. Biopsy of the lesion showed necrosis of tissue with suppuration and histiocytes but no evidence of tuberculosis, fungal infections or atypical mycobacteria. Lymph node biopsy also showed necrosis with suppuration but no infective organism. Nitroblue tetrazolium test was negative indicating that the neutrophils failed to oxidize the dye. We are reporting here a rare case of chronic granulomatous disease.
Assuntos
Biópsia por Agulha , Pré-Escolar , Seguimentos , Doença Granulomatosa Crônica/congênito , Humanos , Imuno-Histoquímica , Masculino , Nitroazul de Tetrazólio/diagnóstico , Doenças Raras , Medição de Risco , Índice de Gravidade de DoençaRESUMO
A retrospective descriptive study of 121 HIV patients in the Department was carried out. The male/female ratio was 2.3:1. The maximum number of patients were seen in age group 21-40 (77.68%). Skilled workers constituted the maximum (13.2%). Sexual route was the commonest mode of transmission (78.5%). Cutaneous manifestations were present in 57% of patients, oral condidiasis being the commonest (16.5%). Pulmonary tuberculosis was the commonest systemic manifestation (13.2%). 37 patients (30.57%) had other STD's, syphilis being the commonest (12.39%). 22 patients had AIDS defining conditions.