RESUMO
Exercise regiments either for healthy life style or for Rehabilitation therapies, cause stresses resulting in physical and metabolic alterations. It is noted that if some of the extremes of exercise were continued for even prolonged periods, it might easily be fatal. In this regard, three metabolic systems are exceedingly significant in understanding the limits of physical activities, viz, the aerobic system, the phosphagen system and glycogen-lactic acid system. During anaerobic metabolism of glucose, and to acquire ATPs for muscular activities, pyruvate is converted into lactic acid, which diffuses out of the muscle cells into interstitial fluids and blood. A high level of lactic acid in blood is hazardous for acid-base balance of the body. Reconstitution of lactic acid, commonly known as removal of lactic acid from the system, is necessary to avoid metabolic acidosis state. This is especially important because lactic acid cause extreme fatigue. Reconstitution of lactic acid takes place mostly through lactic acid-oxygen debt system. Therefore, to monitor proper exercise protocols, lactic acid levels were analyzed in patients undergoing rehabilitation therapies, especially with cardiac and pulmonary abnormalities, such as COPD, CABG etc. Both male and females patients were selected and grouped according to their clinical conditions, age, exercise regiments and duration of rehab. Their blood samples were collected, pre and post-exercise, processed and analyzed according to prescribed methods Control subjects were also passed through same exercise pattern and their blood samples were also analyzed. The results suggest significant importance of this protocol in cardiac and pulmonary rehabilitation and discussed in light of the observations and outcomes