Glomerular diseases outcome at one year in a tertiary care centre

To determine outcome in primary and secondary glomerular diseases at one year follow up. Study design is observational cohort, done in out-patient department, Dow Iinternational Medical College, DUHS. All information gathered on a proforma. All patients with dipstick positive proteinuria and clinical glomerular disease were included in study. Patients with no proteinuria were excluded so were patients with stage 5 CKD. Patients were followed for proteinuria and renal insufficiency at completion of one year follow up. Statistical analysis was done on SPSS version 16. Total number of patients who completed one year follow up was 173. Mean age of patients was 51.67 +/- 10.16 [range 15 to 75 years]. Ninety two [53.2%], were males and 81 [46.8%] were females, ratio being 1.1:1.0. Mean weight of our patients was 67.43 +/- 14.13 Kg, [35 to 107 kg]. Commonest cause of glomerular disease in our patient was diabetic nephropathy which was seen in 94.2% patients. Commonest associated problem with glomerular disease was hypertension seen in 66.5% of patients. Four out of 173 patients had stage 5 CKD at end of follow up at one year while quantitativ proteinuria remained same at one year follow up. One year follow up is critical for patients with glomerular disease associated with stage 4 CKD as progression to end stage renal failure may be seen within one year in these patients

Hemodialysis patients profile at Dow university of health sciences, Karachi, Pakistan

To determine the frequency of diseases contributing to End Stage Renal Failure [ESRF] and to determine the frequency of seropositivity for hepatitis B and hepatitis C in our patients. This is an observational study of two years duration from January 2012 till December 2013, done at Dow university of Health Sciences. Sample size is 189 by convenient method. Data collection is retrospective. Inclusion criteria includes all patients ever hemodialysed at DIMC with age 14 or above. Exclusion criteria is age below 14. Data maintained and analyzed on SPSS version 16. All categorical data in percentages and numeric data is given in frequencies and mean with Standard deviation. Total number of patients included in study were 189, Males were 94/189 [49.7%], females were 95/189 [50.3%], Male to female ratio was 0.98:1.0. Mean age was 51.88 +/- 15.2, range was 14-86 years. Patients started on Hemodialysis were found to have hypertension in 40.2%, both diabetes and hypertension was present in 42.8%, diabetes alone in 3.1% of patients as likely etiology of renal failure. Seropositivity for HBV was found 4/189[2.1%] and HCV in 31/189[16.4%] at initiation of Hemodialysis. Hypertension alone is an important disease found in patients with renal failure as likely cause followed by diabetes. Hepatitis C positivity at start of hemodialysis is 16%