Recurrent familial hydatidiform mole

Gestational trophoblastic disease is rare. Recurrent gestational trophoblastic disease occurs in 0.6-2.6% of subsequent pregnancies. The rate.for a third hydatidiform mole [H.M.] goes up to 15-28%. There are no reliable data on the incidence of consanguinity or family history on the incidence of hydatidiform mole. There have been reports of familial occurence of gestational trophoblastic disease [GTD] in literature. In the case reports presented here two out of a total of four sisters suffered from recurrent hydatidiform molar pregnancies. A third sister was found to have characteristic appearance of a molar pregnancy on ultrasound scan but she ref used treatment. None of these sisters have given birth to a live child

Transcervical endometrial resection for menorrhagia: a review of 117 consecutive cases

A retrospective audit of 117 patients was undertaken in the Department if Gynaecology at City General Hospital, Stoke-on-Trent, U.K. to assess the efficacy of transcervical resection of endometrium [TCRE] in women presenting with menstrual disorders. Patient satisfaction with the procedure was noted at 3, 6, 12 months. A total of 117 TCRE were performed. Three were abandoned in favour of hysterectomy due to major operative complications [2 for perforation of uterus and 1 for uncontrollable bleeding]. Three patients [2.6%] with primary haemorrhage were controlled by tamponade. Glycine toxicity was noted. Of 82 patients followed up for 6 months, 67 [81.7%] had oligomenorrhea or amenorrhoea while among 35 patients followed up for 12 months, 33 [94%] had oligomenorrhea and amenorrhoea. TCRE is a relatively new technique which represents an advance in the management of menstrual problems. Careful audit of results with long term follow up will determine the exact place of this technique in Gynaecology

Can the 32 weeks ultrasound scan be used to predict growth at term: a case-controlled study

This study was undertaken to assess the usefulness of a thirty-two week ultrasound scan in terms of prediction of growth retardation at term. A case-controlled review of 43 growth-retarded [at term] infants was carried out in which the weight at 32 weeks was estimated from biparietal diameter and abdominal circumference and extrapolated to a predicted birthweight. This was strongly correlated with the actual birthweight [r=0.71]. Using a predicted weight of < 2550g as a cut-off point 49 percent growth-retarded infants would have been detected, however cut-off point of < 3000 g would have resulted in over 90 percent of these babies being noted. A single scan at this gestatio is of limited value however because of the high numbers of false positive cases that would be generated. A further scan after a fortnight may be more specific