RESUMO
Analgesic and anti-inflammatory activity of aceclofenac was compared with combination of aceclofenac and paracetamol. The analgesic activity was assessed using Eddy's hot plate method and acetic acid-induced method. The anti-inflammatory activity was assessed in acute [Carrageenan-induced oedema] model of inflammation in rat. The aceclofenac and paracetamol combination showed significant analgesic and anti-inflammatory activity when compared to aceclofenac alone
Assuntos
Animais , Acetaminofen/farmacologia , Quimioterapia Combinada , Anti-Inflamatórios não Esteroides , Analgésicos , Resultado do TratamentoRESUMO
The ethanolic extract of dried leaves of Clerodendron inerme were screened pharmacologically for their hepatoprotective activity against Carbon tetrachloride-induced hepatotoxicity in rats. The ethanolic extract exhibited significant activity by lowering serum levels
Assuntos
Animais , Masculino , Feminino , Fígado/efeitos dos fármacos , Extratos Vegetais , Ratos WistarRESUMO
The analgesic activity was tested by Eddy's hot plate method in albino mice using combination of Pentazocine [1 mg/kg] with Phenytoin [10.20 mg/kg] and Pentazocine [1 mg/kg] with Ketorolac [10.20 mg/kg] was given by intra-peritoneal administration, The results showed a significant increase in reaction time [analgesia] in albino mice and hence the present study indicates that combination of Phenytoin and Ketorolac with Pentazocine has significant prolonged analgesic effect as compared with analgesic effect produced by Pentazocine alone
Assuntos
Animais de Laboratório , Masculino , Feminino , Fenitoína/farmacologia , Cetorolaco/farmacologia , Pentazocina/farmacologia , Camundongos , Medição da DorRESUMO
Honey samples from country drug sellers, street vendors and tribes of Kanchipuram District were subjected to simple Thin Layer Chromatography [TLC] to identify sugars in those samples. Water content estimated by Karl Fischer titration method and refractive indices of the samples found to decrease with an increase in water content