Study of blood pH in ischemic heart disease

Intracellular acidosis acts as an important factor for causing cellular necrosis in patients of ischaemic heart disease. Blood pH and bicarbonate levels were determined in 85 patients of ischaemic heart disease. The patients were classified into myocardial infarction, intermediate coronary syndrome and angina on assessing the clinical and ECG findings. Blood pH was found to be significantly low in patients of myocardial infarction as compared to control. Our result indicated that patients of myocardial infarction developed metabolic acidosis. It is suggested that the acidosis should be corrected as early as possible to prevent myocardial necrosis and extension of infract in ischaemic patien