Metabolic Syndrome and Benign Prostatic Hyperplasia: A Study Focused on the Correlation between Metabolic Syndrome Factors and Prostate Volume and Prostate-specific Antigen / 대한비뇨기과학회지

PURPOSE: To evaluate the relationship between metabolic syndrome and benign prostatic hyperplasia in Korean men, we investigated the relation between prostate volume and the serum prostate specific-antigen (PSA) level with the factors for metabolic syndrome. MATERIALS AND METHODS: We reviewed the data of 1,412 men who had a general health check-up without significant evidence of disease between January 2004 and May 2007. The age, prostate volume, PSA, PSA density and metabolic factors were measured, and the relationships of these factors were evaluated. We also compared the prostate-related data between the metabolic syndrome(MS) group and non-metabolic syndrome(NMS) group. RESULTS: The prostate volume was significantly larger in the MS group (23.0+/-7.1ml) than that in the NMS group(20.9+/-6.1ml)(p<0.001). There was no statistically significant difference of the PSA level between the two groups(MS group: 0.86+/-0.66, NMS group: 0.90+/-0.81), but the PSAD was significantly different between the two groups(MS group: 0.038+/-0.027, NMS group: 0.044+/-0.031)(p=0.0035). We concluded that there was a significant correlation between the prostate volume and the metabolic syndrome factors. However, when analyzing the influence of each metabolic syndrome factor on the prostate volume, only the BMI was a relatively influential factor. CONCLUSIONS: Our study showed that there was significant correlation between each metabolic syndrome factor and the prostate volume. This seemed to be the result of the commonly related pathophysiology of MS and an enlarged prostrate volume, and obesity was a significant factor. It was meaningful that the PSA level in the MS group was lower than that of the NMS group in case of the same prostate volume.

B-cell Lymphoma of the Prostate: Remission with Combination Chemotherapy and Radiotherapy / 대한비뇨기과학회지

A lymphoma of the prostate is very rare, and is usually incidentally discovered. Malignant lymphomas can be divided into either primary or secondary according to their origin. Secondary involvement of the gland is the most common presentation. Most non-Hodgkin's lymphomas that affect the prostate are of the B-cell type, and present with non-specific obstructive symptoms. A variety of methods have been used for their, including prostatectomy, radiotherapy or combinations of chemotherapy and radiotherapy. However, the prognosis remains poor, regardless of the patient's age, histological type, treatment or clinical stage at presentation. Here, the case of a patient with a B-cell lymphoma, who presented with symptoms of a bladder outlet obstruction, is reported. The patient has been in complete remission following the completion of 6 cycles of doxorubicin-based chemotherapy and accompanying radiotherapy.

Metastatic Penile Cancer Originated from Pancreas / 대한비뇨기과학회지

Penile metastases are rare, and usually secondary to other genitourinary primary tumors. Bladder, prostate and renal tumors are the main sources of penile metastasis. Rectal and respiratory neoplasms also metastasize to the penis. However, metastatic penile cancer originating from the pancreas is extremely rare. Here, a case of pancreatic cancer, with penile metastasis, is reported.