RESUMO
Background and Objective: Children spend most of their time in schools and are vulnerable to injuries and mild ailments, hence requiring first-aid care. School teacher can provide immediate first-aid care in the absence of any health professional. This study assesses first-aid facilities within school premises and assessment of teachers on first aid training
Methods: A cross sectional study was conducted from July-December 2017, participants were full time school teachers of both public and private sectors at both primary and secondary levels, having a minimum of one year experience. Questionnaire was filled on one to one basis by taking oral interview
Results: Out of 209 teachers, 72.7% were from private sector. Stomachache was the most common medical incident [82.29%] requiring first-aid care in schools. First aid box was available in all schools but its contents were not satisfactory. Sick bay was not found in any school. 68.42% of teachers were not trained in first-aid management because of lack of opportunity, however 56% were willing to enroll in any first aid training and majority [91.38%] considered it essential for their professional life
Conclusion: First aid facilities at various schools of Karachi and availability of trained teachers who can provide first aid care is unsatisfactory
RESUMO
Objective: To observe the restorative effect of L-arginine on body weight and weight of adrenal glands in streptozotocin [STZ] induced diabetic rats
Methodology: This experimental study was undertaken at the Department of Anatomy, Basic Medical Sciences Institute [BMSI], Jinnah Post graduate Medical Centre [JPMC], Karachi. Fifty healthy albino rats were equally divided into five groups.Group-A was taken as control. Group-B was treated with STZ. Group-C was given STZ with insulin. Group-D received STZ with L-arginine and Group-E was administered STZ along with both L-arginine and insulin. After the confirmation of diabetes by STZ, treatment was continued for a period of 6 weeks. The animals were sacrificed at the end of 6 weeks. At the start and end of the study period mean body weight of animals was calculated. Effect of L-arginine was observed on body weight of animals and weight of adrenal glands and compared with insulin
Results: The decrease in mean body weight of animals due to STZ was less significant when L-arginine and insulin were added to the therapy. Whereas the increase in adrenal glands weight was also less marked on administering L-arginine and insulin
Conclusion: L-arginine has restorative effect on gross morphology and weight of adrenal glands which is comparable to insulin
RESUMO
AIM@#The hypoglycemic and hypolipidemic effects of the methanol extract of Brassica oleracea var. capitata (MEB) was evaluated in alloxan-induced diabetic rabbits.@*METHOD@#The study was conducted on twenty-eight healthy white rabbits of either sex. All animals were equally divided into four groups. After confirmation of hyperglycemia, the animals of the treated and standard groups were administered MEB (500 mg·kg(-1)) and glibenclamide (10 mg·kg(-1)), respectively for 15 and 30 days. The animals of the normal and diabetic controls received normal saline 1 mL/day equivalent to the volume of doses given to the test and standard animals. Biochemical tests were performed at the end of dosing, i.e. the 16(th) and 31(st) days.@*RESULTS@#The MEB revealed a decrease of 106.6 mg·dL(-1) in fasting blood glucose as compared to diabetic control, which was almost comparable to glibenclamide; both of these changes were highly significant. The decrease in total cholesterol and low density lipoprotein was 94.3 and 96.5 mg·dL(-1), respectively, whereas the high-density lipoprotein was increased by 26.7 mg·dL(-1), as compared to diabetic control. All of the changes in lipid profile were statistically significant.@*CONCLUSION@#These results suggest the potential of MEB as a hypoglycemic and hypolipidemic agent.