Research on return visit and investigation of the relapse rate of children allergic purpura after treatment

This paper aimed to research on return visit and investigation of the relapse rate of children allergic purpura after treatment. Children with allergic purpura were divided into two groups. The treatment group was treated with the adrenocorticotrophic hormone while the control group did not. We tracked and observed two groups of discharged children in the first month and the second month. It can be found that, at the first month, 5 cases recurred in the treatment group with 20 cases, the relapse rate was 25%, 1 case recurred in control group, the relapse rate was 5%; at the second month, 2 cases recurred in treatment group, the relapse rate was 10%, no case recurred in the control group. There were 8 cases recurred in the past two months, and there were no replase after the second time treatment. In contrast, the children, who treated with adrenocorticotrophic hormone, had higher relapse rate, while the control group had lower relapse rate. Then we can get the conclusion that, the application of adrenocorticotrophic hormone may be one of the main reasons to induce the allergic purpura and we should notice and discuss this conclusion in the clinical practice

Effect of lactoferrin supplementation combined with standard therapy on Helicobacter pylori infection in children / 临床儿科杂志

Objective To observe the effect of lactoferrin supplementation combined with standard triple therapy on eradication rate of Helicobacter pylori (H.pylori) and its adverse reaction in children. Methods A total of 90 children who were diagnosed with H.pylori infection from January 2012 to January 2013 and had never received eradicative treatment were ran-domly divided into two groups. Forty-five children in control group received the standard triple therapy and another 45 children in observation group received lactoferrin supplementation combined with standard triple therapy. Adverse reaction during the treatment was recorded and eradication rate of H.pylori at 4 weeks after treatment was observed. Results The eradication rate of H.pylori in observation group (91.11%, 41/45) was higher than that in control group (73.33%, 33/45) and the adverse reaction rate in observation group (4.44%, 2/45) was lower than that in control group (20.00%, 9/45).The differences were significant (P<0.05). Conclusions Lactoferrin supplementation combined with standard triple therapy can increase H.pylori eradication rate and reduce the occurrence of adverse reaction.