Relación entre actividad física, rendimiento académico y funciones ejecutivas en adolescentes: una revisión sistemática / Relationship between physical activity, academic performance and executive functions in adolescents: a systematic review / Relação entre atividade física, Rendimento acadêmico e funções executivas em adolescentes: uma revisão sistemática

El objetivo de este estudió fue analizar la producción científica actual sobre el nivel de actividad física, rendimiento académico y funciones ejecutivas, con el fin de relacionar los beneficios del ejercicio con los procesos cognitivos de escolares. Metodología: Para la revisión y selección de artículos, se siguió la metodología de revisión sistemática basada en las declaraciones internacionales PRISMA. Las principales bases de datos utilizadas son; Dimensions, LILAC, PubMed, Scielo, Scopus y Dialnet. Búsqueda de artículos de intervención y de revisión publicados entre 2013 y 2020, con un rango etario de 10 a 18 años y escritos en idioma español. Los resultados indican que los estudios centran sus objetivos en analizar y comparar las relaciones entre las variables AF, RE y FE. Se concluye que existe una influencia positiva de la actividad física sobre las variables de rendimiento académico y funciones ejecutivas, lo que se traduce principalmente en una mejora en matemáticas y/o lectura, en la memoria y la atención.

The objective of this study was to analyze the current scientific production on the level of physical activity, academic performance, and executive functions, in order to relate the benefits of exercise to the cognitive processes of schoolchildren. Methodology: For the review and selection of articles, we followed the systematic review methodology based on the PRISMA international declarations. The main databases used are: Dimensions, LILAC, PubMed, Scielo, Scopus, and Dialnet. The search focused on intervention and review articles published between 2013 and 2020, with an age range of 10 to 18 years old and written in Spanish. The results indicate that the studies focus their objectives on analyzing and comparing the relationships between the FA, AP, and EF variables. It is concluded that there is a positive influence of physical activity on the variables of academic performance and executive functions, which mainly translates into an improvement in mathematics and/or reading, as well as in memory and attention.

O objetivo deste estudo foi analisar a produção científica atual sobre o nível de atividade física, rendimento acadêmico e funções executivas, a fim de relacionar os benefícios do exercício físico com os processos cognitivos de escolares. Metodologia: para a revisão e seleção dos artigos, seguiu-se a metodologia de revisão sistemática baseada nas declarações internacionais PRISMA. As principais bases de dados utilizadas são: Dimensões, LILAC, PubMed, Scielo, Scopus e Dialnet. Pesquisa de artigos de intervenção e revisão publicados entre 2013 e 2020, com faixa etária de 10 a 18 anos e escritos em espanhol. Os resultados indicam que os estudos focam seus objetivos em analisar e comparar as relações entre as variáveis AF, RE e FE. Conclui-se que existe uma influência positiva da atividade física nas variáveis de desempenho acadêmico e funções executivas, o que se traduz principalmente em melhora em matemática e/ou leitura, em memória e atenção.

Esclerosis múltiple: reacciones adversas a medicamentos en pacientes bajo ley 20850, Hospital Regional de Talca / Multiple sclerosis: adverse drug reactions in patients under law 20850, Hospital Regional de Talca

INTRODUCTION: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system, which occurs in up to 85% of cases as relapsing remitting (RR), with episodes of neurological dysfunction partially forwarded. Its treatment in Chile is financially protected by the Explicit Health Guarantees (GES) and Law 20,850 on high-cost diseases. The Regional Hospital of Talca (HRT) has 25 patients benefiting from Law 20,850 in treatment with second-line biologic therapy. Adverse reactions (RAM) to the use of these drugs have been described and to date there are no case reports or studies of significant adverse events in Chile. Objectives: To present the experience of the use of biologic therapy in EMRR in HRT, in relation to adverse events. METHODS: A review of the current guidelines in Chile for the treatment of relapsing-remitting multiple sclerosis and the protocol of law 20,850 was carried out, the clinical records of 25 patients benefiting from the law in the HRT were reviewed, with emphasis on the adverse events presented before First and second line therapies and the con sequences of these events on the continuity of therapy. RESULTS: Half of the patients who started their treatment with first-line drugs had adverse effects, of which 28% involved a change in therapy, the remaining changed from therapy due to failure to treatment. Of the 26 patients included in the sample, 24 are currently using second-line drugs. The profile of adverse effects should be a variable to consider when indicating a therapy for MS.