RESUMO
OBJECTIVE: To determine the efficiency of probing in partial nasolacrimal duct obstruction [NLD] in adults
STUDY DESIGN: Prospective study
PLACE AND DURATION OF STUDY: Department of Ophthalmology unit 1, Dow University of Health Sciences, Civil Hospital Karachi from January 2006 to July 2011
METHODOLOGY: This study includes 340 patients complaining of watering of the eye for more than 6 months duration from partial NLD obstruction. Eye examination was done to exclude other causes of watering. ENT opinion was taken to exclude nasal pathology. Risk and benefits of probing were explained to all patients and their written consent was taken. Probing was done in operation theatre under aseptic conditions in local anaesthesia. Probe was left in place for 02 minutes to allow dilatation of nasolacrimal duct. Post probing, patients were given topical antibiotics for 1 week and were followed for a period of 06 months
RESULTS: Out of 340 patients only 35 [10.3%] patients became asymptomatic, rest of the patient came back with epiphora within 02 months
CONCLUSION: Probing of NLD in adults for partial obstrution gives symptomatic relief only in a few cases and majority of patients need surgical intervention
RESUMO
Objective: To document the clinical presentation and fundus fluorescein angiographic findings in Stargardt's disease
Methodology: This descriptive study was conducted at the Department of Ophthalmology Unit-I Civil Hospital Karachi and Unit III Lyari General Hospital Karachi of Dow University of Health Sciences from June 2004 to May 2008. Patients were selected from the out patient department of Sindh Govt. Lyari General Hospital and Civil Hospital Karachi fulfilling the inclusion criteria. Sociodemographic data and family history were obtained and patients subjected to complete ophthalmic examination of anterior and posterior segment and Fundus Fluorescein Angiography
Results: Thirty patient were found to have Stargardt's disease. Mean age was 18.4 +/- 6.9 years. Twenty two [73.4%] patients were found to be 20 years of age or below. Males [18 [60%]] outnumbered the females [12[40%]]. Visual acuity at presentation revealed a symmetric loss of vision in right and left eyes [P=0.410 at 99% CI]. Macula showed atrophic lesion in 12 cases [40%], beaten bronze in 13 [43.3%] cases and varnished appearance in 5 [16.7%] cases. Retinal flecks were found in 18 [60%] patients only. Fundus fluorescein angiography revealed dark choroids and elliptical hyperfluorescent lesion at the macula in all the patients. Tiny hyperfluorescent areas not corresponding to the area of flecks were found only in 18 [60%] patients
Conclusion: We conclude that Stargardt's disease has varied presentation and there is a familial and genetic predilection