RESUMO
Background: Sugar- and artificially-sweetened beverage consumption have been connected to cardio metabolic hazard factors, which rise the danger of cerebrovascular illness and dementia
Purpose: We studied whether sugar or artificially sweetened beverage intake was related with the prospective dangers of incident stroke or dementia
Materials and methods: We studied 361 members aged more than 45 years for incident stroke [mean age 61 [SD, 10] years; 163 men] and 185 participants aged >60 years for incident dementia [mean age 68 [SD, 7] years; 85 men]. Beverage consumption was computed using a food-frequency questionnaire at cohort studies. We quantified latest consumption at investigation 7 and cumulative intake by averaging across examinations. Surveillance for incident events commenced at examination 7 and continued for 5 years. We observed 12 cases of incident stroke [10 ischemic] and 10 cases of incident dementia [8 consistent with Alzheimer's disease]
Results: After modifications for age, gender, education [for analysis of dementia], caloric consumption, diet feature, physical activity, and smoking, higher recent and higher cumulative consumption of artificially sweetened soft drinks were related with an increased risk of ischemic stroke, all-cause dementia, and Alzheimer's disease dementia. When comparing day-to-day aggregate consumption to 0 per week [reference], the risk ratios were 2.87 [95% confidence interval, 1.24-6.89] for ischemic stroke and 2.91 [95% confidence interval, 1.15-6.99] for Alzheimer's disease. Sugar-sweetened beverages were not associated with stroke or dementia
Conclusions: Artificially sweetened soft drink consumption was allied with a higher risk of stroke and dementia