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Chinese journal of integrative medicine ; (12): 760-766, 2021.
Artigo em Inglês | WPRIM | ID: wpr-922118

RESUMO

OBJECTIVE@#To investigate the molecular mechanisms underlying the effects of arsenic trioxide (As@*METHODS@#Transplantation of LVG hamster hearts to Lewis rats was performed by anastomosis of vessels in the neck using end-to-end anastomosis with a non-suture cuff technique. Four groups of recipient rats (n=6 in each) were treated with normal saline (control), As@*RESULTS@#Expression of Nrf2-ARE-HO-1 signaling pathway was upregulated in heart xenografts in rats treated with As@*CONCLUSION@#Combination treatment with As


Assuntos
Animais , Cricetinae , Ratos , Trióxido de Arsênio , Transplante de Coração , Heme Oxigenase-1/metabolismo , Xenoenxertos , Leflunomida , Fator 2 Relacionado a NF-E2/metabolismo , Ratos Endogâmicos Lew , Transdução de Sinais
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