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Mem. Inst. Oswaldo Cruz ; 104(4): 621-625, July 2009. tab
Artigo em Inglês | LILACS | ID: lil-523730

RESUMO

Significant advances were made in the diagnosis of filariasis in the 1990s with the emergence of three new alternative tools: ultrasound and tests to detect circulating antigen using two monoclonal antibodies, Og4C3 and AD12-ICT-card. This study aimed to identify which of these methods is the most sensitive for diagnosis of infection. A total of 256 individuals, all male and carrying microfilariae (1-15,679 MF/mL), diagnosed by nocturnal venous blood samples, were tested by all three techniques. The tests for circulating filarial antigen concurred 100 percent and correctly identified 246/256 (96.69 percent) of the positive individuals, while ultrasound detected only 186/256 (73.44 percent). Of the circulating antigen tests, ICT-card was the most convenient method for identification of Wuchereria bancrofti carriers. It was easy to perform, practical and quick.


Assuntos
Adolescente , Adulto , Idoso , Animais , Criança , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Anticorpos Anti-Helmínticos , Anticorpos Monoclonais , Antígenos de Helmintos/sangue , Filariose Linfática/diagnóstico , Microfilárias/ultraestrutura , Wuchereria bancrofti/imunologia , Ensaio de Imunoadsorção Enzimática , Filariose Linfática/sangue , Filariose Linfática , Sensibilidade e Especificidade , Adulto Jovem
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