RESUMO
The objective of this study was to determine the prevalence of impaired glucose regulation in a young, asymptomatic Kuwaiti population. A cross-sectional study of 484 Kuwaitis [females: 311, and males: 173, aged 17-24 years], students at a public college for basic education, was conducted. Each participant underwent a 75-gram oral glucose tolerance test, and biochemical testing for hemoglobin A[1c] [HbA[1c]], total cholesterol and triglyceride levels. Physical examinations were performed to measure body mass index [BMI], waist circumference and blood pressure. The prevalence of impaired glucose regulation [impaired fasting glucose, impaired glucose tolerance, and elevated HbA[1c] levels] was 32%, including 4% with newly diagnosed diabetes. Of the 484 participants, 47 [10%] of the population had hypertension and 52 [11%] had dyslipidemia. A total of 244 [50%] were classified as overweight/obese [BMI>25 kg/m[2]] and 201 [42%] had an elevated waist circumference [>/=88 cm in females;>/=102 cm in males]. Impaired glucose regulation was significantly related to increased waist circumference [p=0.021] but not to increased BMI [p=0.181]. Those with impaired glucose regulation also had a higher prevalence of hypertension [p=0.05], particularly systolic hypertension [p=0.023]. Kuwaiti youth have a high prevalence of impaired glucose regulation and overweight/obesity. Waist circumference, rather than BMI, may be a more
RESUMO
A growing number of reports suggest a connection between hepatitis C virus [HCV] infection and type 2 diabetes [T2D]. However, the association of HCV infection with diabetes-related complications has not yet been clarified. The aim of this study was to determine the prevalence of HCV infection in T2D-patients in Kuwait which has a high incidence of type 2 diabetes, and to investigate the association between HCV viremia and diabetes-related complications. A total of 438 patients with T2D [325 Kuwaitis and 113 Egyptians], and 440 control subjects, were enrolled for this study. HCV infection was assessed by testing for serum HCV-specific antibodies, and by detection of HCV RNA. HCV viral load and hemoglobin A1c [HbA1c] levels were assessed in patients with and without diabetes complications. Thirty one [7%] out of 438 T2D-patients had evidence of HCV infection compared to 4 [1%] out of 440 control adults [p < 0.0001]. The prevalence of HCV infection in Kuwaiti and Egyptian T2D-patients was 3% and 18%, respectively. Most of the HCV sequences detected in T2D patients and control subjects were of genotype 4. The HbA1c levels in T2D-patients with HCV viremia were significantly higher than those in HCV-negative patients. HCV viremia, female sex, age, family history of diabetes were found to be independent risk factors for diabetes complications. The results suggest that T2D-patients in Kuwait have higher prevalence of HCV infection than controls, and that HCV viremia is associated with diabetes-related complications
RESUMO
To study the effect of Ramadan fasting in type 2 diabetic patients on the control of diabetes, blood pressure, dyslipidemia and body weight. Observational prospective study conducted in month of Ramadan year 2006. The subject: 36 patients were asked to enroll in the study all were T2DM on either diet control alone or diet and oral anti diabetic therapy [NOT on Insulin], only 16 completed the whole study. Patients were selected randomly from diabetes out-patient of Alamiri hospital. Patients were studied before [within a month before Ramadan] and at the end of Ramadan [within the last 5 days of the month] for the following variables: Body weight, Blood Pressure, HbAlc, Total cholesterol, LDL cholesterol, HDL cholesterol, Triglycerides and the total daily caloric intake. We found no significant changes in the total daily caloric intake, weight, glycaemic control, blood pressure, and lipid control. Ramadan fasting in the current dietary pattern did not lead to significant changes in the control of diabetes, blood pressure, dyslipidemia, and body weight in patients with T2DM