RESUMO
Diabetes Mellitus is a chronic disease prevalent worldwide with an increasing frequency of occurrence. Diabetes produces a wide array of symptoms throughout the body. It is said that mouth is the mirror of systemic health. The effects of diabetes are most frequently reflected in the oral cavity. Gingivitis and periodontitis are most frequently associated with diabetes. Periodontitis has been reported as sixth complication of diabetes and they both exhibit a bidirectional interrelationship. This article reviews about the oral lesions occurring in diabetes and their pathogenesis. This article also focuses on the interrelationship between diabetes and oral health stressing the need for oral health assessment and treatment as part of preventive medical therapy for diabetes.
RESUMO
The aqueous extract of S. cumini or Eugenia jambolana seeds and Psidium guajava leaves showed higher inhibition against the porcine pancreatic alpha-amylase among the medicinal plants studied. The alpha-amylase inhibitors from S. cumini seeds were separated from the extract by preparative thin layer chromatography into fractions with different Rf values. The fraction with Rf value between 0.285 and 0.43, which showed maximum inhibitory activity, was eluted and analyzed through LC-MS. The compounds identified from the seed extract ofS. cumini were betulinic acid and 3,5,7,4'-tetrahydroxy flavanone, which were reported earlier from S. formosanum and other plants. Dixon plot showed that the inhibition was noncompetitive in nature.