RESUMO
One male patients presenting with symptoms and signs of atrophic rhinitis and chronic sinusitis for one year, there was also a small red mass at anterior end of right middle turbinate. Histopathological section showed that the mass was covered by stratified squamous mucosa with diffuse cellular infiltration of mostly macrophages with clear vacuolated cytoplasm (= foam cells) with few lymphocytes in submucosa. Acid fast stain (modified Fite Feraco stain) showed numerous acid fast bacilli in scatter and in clumps, known as globi pattern mucosa. This is the first case reported in Thailand. Multidrug therapy was given to the patient which conprised of rifampicin 450-600 mg. Once a month, lamprene 300 mg start and then 100 mg. in alternate day with dapsone 100 mg. OD. The aim of this report is to remind the otolaryngologists of the existence of leprosy in the nose and they should be aware of the highly contagious nasal secretion from these patients.