RESUMO
An eight-year-old male child presenting with history of generalized convulsions, gradual loss of speech and generalized EEG (electroencephalography) abnormalities was diagnosed as Landau Kleffner Syndrome. He initially developed generalized convulsions which later changed to partial seizures during the course of illness. He was started on sodium valproate and continued with the drug (30 mg/kg/day) on which, he showed improvement in speech, behavior, hyperkinesis and frequency of convulsions during the follow-up.
Assuntos
Criança , Diagnóstico Diferencial , Eletroencefalografia , Humanos , Síndrome de Landau-Kleffner/diagnóstico , Masculino , Ácido Valproico/uso terapêuticoRESUMO
This paper explores the relationships between maternal weight, height and poor pregnancy outcome using a data set from a case-control study of low birth weight (LBW) and perinatal mortality in Ahmedabad, India. Maternal height and weights were compared between mothers of 611 perinatal deaths, 644 preterm-LBW, and 1465 normal birth weight controls as well as 617 small-for-gestational age (SGA) and 1851 appropriate-for-gestational-age (AGA) births. Weight and height were much lower in this population compared to western standards. Low weight and height were associated with increased risk of perinatal death, prematurity and SGA. After adjusting for confounders, maternal weight remained significantly associated with poor pregnancy outcomes, whereas height was only weakly associated. Attributable risk estimates show that low weight is a much more important contributor to poor outcome than low height. Improvement in maternal nutritional status could lead to substantial improvement in birth outcome in this population.
Assuntos
Peso ao Nascer , Estatura , Peso Corporal , Estudos de Casos e Controles , Feminino , Humanos , Índia/epidemiologia , Mortalidade Infantil , Recém-Nascido de Baixo Peso , Recém-Nascido , Recém-Nascido Prematuro , Recém-Nascido Pequeno para a Idade Gestacional , Estado Nutricional , Gravidez , Resultado da Gravidez , Fatores de RiscoRESUMO
A review of postabortal sepsis following a 2-year study undertaken at the Department of Obstetrics and Gynaecology, SSG Hospital, Baroda is presented here with a view to know the incidence of postabortal sepsis and septic induced abortions and to re-evaluate the effectiveness of the MTP services in reducing its impact on maternal morbidity and mortality, since the implementation of the MTP Act in 1972. It has been observed that postabortal sepsis is a major cause of maternal mortality even now and MCH service is to be improved to reduce the same.
Assuntos
Aborto Criminoso , Aborto Séptico/complicações , Aborto Espontâneo/complicações , Feminino , Humanos , Infecções/etiologia , GravidezAssuntos
Adolescente , Encéfalo/anormalidades , Encefalopatias/genética , Córtex Cerebral/anormalidades , Ventrículos Cerebrais/anormalidades , Criança , Cistos/genética , Feminino , Hemiplegia/genética , Humanos , Masculino , Deficiência Intelectual/genética , Exame Neurológico , Tomografia Computadorizada por Raios XRESUMO
A case of paraganglioma of the cauda equina is presented. Usually reported to be benign with good prognosis, the present patient had a somewhat different course. The behaviour of the tumour was unusual, with rapid recurrence seen within first month of surgery. The need for total surgical excision and role of adjuvant radiotherapy is highlighted.
Assuntos
Cauda Equina , Terapia Combinada , Feminino , Humanos , Pessoa de Meia-Idade , Paraganglioma/terapia , Neoplasias do Sistema Nervoso Periférico/terapiaAssuntos
Adulto , Feminino , Humanos , Índia , Recém-Nascido de Baixo Peso , Recém-Nascido , Masculino , GravidezRESUMO
Benzamido (alkyl) methyl pyrrolidine Mannich bases were synthetized and subjected to certain neuropharmacological studies. All the bases reduced the pentobarbitone sleeping time and rota-rod grip of rats. The Mannich bases II, III and V raised the minimal electro-shock seizure threshold of rats. The TAB-induced pyrexia was not reduced by the bases I and III in rabbits. None of the bases showed any significant analgesic activity.
Assuntos
Aminas/farmacologia , Animais , Temperatura Corporal/efeitos dos fármacos , Encéfalo/efeitos dos fármacos , Masculino , Bases de Mannich/farmacologia , Pentobarbital/farmacologia , Equilíbrio Postural/efeitos dos fármacos , Coelhos , Ratos , Receptores de Droga/metabolismo , Limiar Sensorial/efeitos dos fármacos , Sono/efeitos dos fármacos , Fatores de TempoAssuntos
Adolescente , Adulto , Fatores Etários , Idoso , Animais , Mordeduras e Picadas/complicações , Criança , Pré-Escolar , Cães/fisiologia , Extremidades , Feminino , Humanos , Imunização/métodos , Índia , Masculino , Pessoa de Meia-Idade , Cooperação do Paciente , Raiva/tratamento farmacológico , Vacina Antirrábica/uso terapêutico , Estações do Ano , Fatores SexuaisAssuntos
Adolescente , Adulto , Estatura , Peso Corporal , Feminino , Humanos , Índia , Masculino , Estudantes , UniversidadesRESUMO
Intraventricular injection of histamine and normal saline in rats caused a marked fall in adrenal ascorbic acid indicating a stimulatory effect of both on pituitary adrenal axis. Intraventricularly injected histamine caused significant hypoglycaemia also in rats as compared to control series.