RESUMO
Objective: To identify maternal factors associated with intrauterine growth restriction [IUGR]
Study Design: A case-control study
Place and Duration of Study: Neonatal Unit of The Aga Khan Hospital for Women [AKHW], Karimabad, from January 2014 to December 2015
Methodology: Cases were IUGR live born babies [n=90], while control were appropriate-for-gestational age [AGA] babies [n=180]. Information recorded in pre-designed proforma included gestational age and birth weight of baby, demographics of mothers, pregnancy related medical and obstetric complications. Data were analysed through SPSS-19. Multivariable logistic regression was used to determine the maternal factors associated with the intrauterine growth restriction
Results: Maternal factors associated with IUGR after adjusting for confounders in the multivariable model included younger age [OR=0.9, CI=0.8-0.9], poor gestational weight gain [OR=3.0, CI=1.6-6.1] and history of previous abortion [OR=3.06, CI=1.1-8.0]. Significant interaction was found between pregnancy-induced hypertension [PIH] and parity of mother, primary-para mother with PIH having an increased risk for IUGR babies [OR=10.1, CI=1.0-23.2]
Conclusion: Young age, primigravida status, low gestational weight gain, previous history of abortion, PIH and GDM have strong association with IUGR; hence, special consideration is essential to overcome these issues in order to improve maternal and neonatal health